CombiScope 1000 - Combining Scanning Probe Microscopy (SPM) with Inverted Optics by AIST-NT

Topics Covered

Introduction
CombiScope 1000 from AIST-NT
Stable Focus-Tip Alignment
Open Access and Head Placement/Removal
CombiScope 1000 Brings Nanoscale Screening to Medical and Pharmacy Laboratories
Open Architecture of CombiScope 1000

Introduction

For the recent years Scanning Probe Microscopy (SPM) has proved to be the extremely successful technique for characterization of different nano-sized objects. SPM plays the important role in the outburst of scientific and commercial activities defined by the term"nanotechnology". As a great number of applications for the SPM-based research are becoming more and more diverse and complex, new challenges and demands arise for the SPM instrumentation. Unfortunately, still the adjustment of the most modern SPMs iscomplicated, time consuming and very much operator-dependant. This drawback leads to poor reproducibility of the instrument settings and consequently to poorly reproducible results.

CombiScope 1000 from AIST-NT

The AIST-NT CombiScope 1000 is designed to combine Scanning Probe Microscopy with inverted optics. The combiscope is the entry path for researchers in biology, spectroscopy and photonics, who work with transparent samples either in air or in liquid, towards nano-scale structures and (near-field) nano-optical properties. Specially for this group of users, the concept of automation is of crucial importance.

Stable Focus-Tip Alignment

The added value for combining SPM with optics in general is that the very same spot of the sample is evaluated simultaneously by the focused optics and the SPM tip. The only real stable alignement during the full time of the analysis is achieved only then when both tip and focus don't move at all. Therefore any solution where either of both are part of the surface tracking process is failing this criteria. Though for alignment purposes both tip and focus can be positioned through motorized control, in the CombiScope 1000 solution only the sample is scanning. As such the sample is scanned ideally through the perfectly aligned Tip-Focus spot.

Open Access and Head Placement/Removal

With the AIST-NT CombiScope 1000 one enjoys the convenience of the over-all AIST-NT SPM automation. With a click of a button the SPM head parks away from the entire sample area and opens up space for free and easy sample replacement or modification. This last piece of automation makes the system Glove Boc Compatible. Together with a set of prepared cantilever holders that can be replaced while wearing the rubber gloves, one can operate the CombiScope 1000 in any controlled gas or bacterilogical closed environment.

CombiScope 1000 Brings Nanoscale Screening to Medical and Pharmacy Laboratories

The CombiScope 1000 brings nano-scale screening to medical and pharmacy laboratories. For the first time in history early diagnosis can be based on nano-scale dicease recognition. The complete instrument automation brings back the job to simple sample exchange. Special sample holders with pre-alignment facilities can be delivered on customers specification.

Open Architecture of CombiScope 1000

The open architecture of the CombiScope 1000 opens up the path to couple with high-speed confocal systems of well known vendors. Like with the Nikon Eclipse C1 Plus modular confocal system with superior scan head optics, faster image acquisition capabilities and improved control over illumination intensity.

Source: AIST-NT

For more information on this source please visit AIST-NT

Date Added: Mar 4, 2009 | Updated: Jun 11, 2013
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