Viral Purification with a-TCP Nanoparticles
Nanograde is the leading supplier of customized nanoparticles. Nanograde's technology allows the fine-tuning of certain properties into polymer additives. Different leaders-in-the-field entrusted Nanograde with the development of tomorrow's material solutions.
Besides being perfectly suited for bone regeneration applications, Nanograde’s amorphous tricalcium phosphate nanoparticles (a-TCP) show a high binding capacity to viral particles. The viral particles can easily be collected after purification by detachment of the a-TCP particles by the use of specific buffer detergents.
A-TCP nanoparticles and other biomedical and degradable nanoparticles are commercially available at Switzerland based Nanograde Llc. In addition to highly pure a-TCP nanoparticles, the composition can be altered with additional doping elements. Nanograde’s strong technology and knowhow allows customization of nanoparticle compositions and dispersions enabling the inclusion of additional properties.
Figure 1. TEM picture of amorphous calcium phosphate (a-TCP) nanoparticles.
Figure 2. a-TCP nanoparticles immobilizing two viral particles.
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