The R&D of BBInternational's Gold Colloid Reagent

By AZoNano

Table of Contents

Introduction

BBI gold colloids have been used for more than 20 years because of its excellent performance and quality and features in more than 400 million tests in the global market place every year. A large number of these have FDA cleared status. Gold particles have superior stability and sensitivity characteristics and since the market has expanded to anticipate higher sensitivity levels gold is being considered as a highly reliable raw material in offering a precise visual signal.

Creating Superior Quality Colloidal Gold

Gold colloid is an ideal reagent used in the manufacture and development of assays since a range of particle sizes can be used for a number of applications. This reagent is inert and forms uniform spherical particles of any size.

The meticulous processes ensure that gold reagents are of superior quality, irrespective of the particle size. This flexibility combined with the superior binding properties of gold to proteins makes gold the preferred label in a large number of rapid tests whether dry or wet.

Colloidal gold from BBInternational is offered in a broad range of pre-determined sizes and is supplied in a form ready for conjugation in a range of concentrations with measurements in optical density units of 520 nm outer diameter. The colloidal gold has a 12-month shelf life when stored unopened at 4°C.

The key advantages of BBI's Colloidal Gold, which is a market leading product are:

• Stability and Sensitivity
• Low Coefficient of Variation (<8%)
• Uniform shape and size
• Roundness (>95 % spherical, <5% uneven shapes)

Gold Colloid Sizes Available from BBInternational

Gold colloids are manufactured by BBInternational in the following sizes making sure that customer needs are catered whatever the application.

Gold Colloid Volumes Available from BBInternational

Bulk Gold colloids are provided by BBI from 100 ml to 350 l from a single batch ensuring product consistency.

The BBI Difference

The specialties of BBI are:

• The company’s innovative gold formula helps in consistently manufacturing high quality gold colloid to a range of size specifications to satisfy most diagnostic applications.
• The proprietary manufacturing technique of BBInternational enables regular production of large gold batches to an exclusively high level of repeatability in terms of dispersion, size and shape. This ensures a firm foundation for conjugation and the peace of mind that the rapid assay will offer reliable results.

It is important that the gold colloid clears a rigorous quality control procedure before being supplied to the customers. Due to these stringent quality procedures at BBInternational, these high performance characteristics will be achieved with typical batch size of up to 200 l.

Superior gold colloid is a vital component of successful lateral flow tests

Good Gold - BBI

Optimum Sensitivity

The uniform size and shape of BBInternational gold colloid ensures that it remains aggregate free. With maximum surface area, it offers optimum conditions for conjugation, and therefore optimum antibody activity.

Guaranteed Stability

A combination of extremely high percentage singlet gold particles and uniform shape maximises the stability of BBInternational gold, ensuring consistency of product with guaranteed stability for up to 12 months. Customers can choose any size gold colloid and be confident that each batch of gold is the same every time.

About BBInternational

BBInternational is recognised globally for the design and manufacture of superior quality gold reagents applied within lateral flow rapid diagnostic tests for the 'Point of Care' (POC) market. BBInternational offers its unique 'in-house' recipe gold colloid to a major player in the global diagnostics marketplace with a reputation for its superior quality reagents, assay development, and contract manufacturing services.

This information has been sourced, reviewed and adapted from materials provided by BBInternational.

For more information on this source, please visit BBInternational.