The Mitos
Resealable Chip Interface is used in combination with microfluidic chips that
can
be opened and resealed. The chip base layer is loaded into the holder first
followed by the
gasket and then the chip top layer. The holder clamps the layers together and
provides
eight fluidic and eight electrical connections to the chip.
Reagents, sensors, biosensors or cells can be deposited on the chip base layer.
The chip
base layer material is typically glass, quartz, or polymer. Fluids are then
flowed through
channels in the gasket layer over the deposited sensors or reagents. The depth
of the
channels in the gasket is typically between 100 – 500 microns. Applications
include:
biosensor testing, cell culture and analysis, dielectrophoresis experiments
and impedance
detection.
Chip Design
The windows at the top and bottom of the holder allow a microscope objective
lens to get
within millimetres of the microfluidic channel structure. The exact distance
depends on the
channel size.
Benefits
- Low profile allows viewing with a microscope
- Excellent chemical resistance
- Easy to clean
- Eight fluidic and eight electrical connections
- Allows deposition of reagents, sensors or cells onto channel surface