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New Type of Injectable Self-Healing Nanogel for Drug Delivery

New Type of Injectable Self-Healing Nanogel for Drug Delivery

Scientists are interested in using gels to deliver drugs because they can be molded into specific shapes and designed to release their payload over a specified time period. However, current versions aren’t always practical because must be implanted surgically. [More]
Manhattan Scientifics Reacquires All Rights to Nano-Structured Metals Technology

Manhattan Scientifics Reacquires All Rights to Nano-Structured Metals Technology

Manhattan Scientifics, Inc. has reacquired all rights in its nano-structured metals technology from its former Licensee whose strategic corporate priorities had changed. The agreement includes a one-time payment to Manhattan of $8 million, the assignment to Manhattan of all related IP and the transfer of ownership of various ECAP machinery and equipment used in the manufacturing process of nano-structured metals. The additional non-cash value of this transaction exceeds $10 million. [More]
Biodegradable Nano 'Drones' Could Prevent Heart Attacks Caused By Atherosclerosis

Biodegradable Nano 'Drones' Could Prevent Heart Attacks Caused By Atherosclerosis

Nanometer-sized "drones" that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, according to a study in pre-clinical models by scientists at Brigham and Women's Hospital (BWH) and Columbia University Medical Center. These findings are published in the February 18th online issue of Science Translational Medicine. [More]
Antimicrobial Silver Nanoparticles Induce Stress in the Endoplasmic Reticulum, Demonstrating Nanotoxicity

Antimicrobial Silver Nanoparticles Induce Stress in the Endoplasmic Reticulum, Demonstrating Nanotoxicity

Whereas resistance to antibiotics complicates certain treatments, antimicrobial silver nanoparticles (AgNP) are gaining popularity for medical use. These particles are toxic for certain bacteria, but what about for humans? Researchers at INRS-Institut Armand-Frappier Research Centre have taken a step toward understanding the cellular and molecular mechanisms that affect these particles. [More]
Conventional Patch-Clamp Technique Combined with AFM Helps Record Activity of Moving Cells

Conventional Patch-Clamp Technique Combined with AFM Helps Record Activity of Moving Cells

Electrical impulses play an important role in cells of the human body. For example, neurons use these impulses to transmit information along their branches and the body also uses them to control the contraction of muscles. [More]
NanoGap Sensor Device for Early Detection of Bladder and Kidney Cancer

NanoGap Sensor Device for Early Detection of Bladder and Kidney Cancer

A new mobile device that allows bladder and kidney cancer to be detected at an early stage. This is being worked on by Wilfred van der Wiel, professor of nanoelectronics at the University of Twente MESA+ research institute. Thanks to this method, it is possible to read from DNA cells whether their carrier has bladder or kidney cancer. [More]
Baxter Provides Update on Gene Therapy Program for Hemophilia B at EAHAD Annual Congress

Baxter Provides Update on Gene Therapy Program for Hemophilia B at EAHAD Annual Congress

Baxter International Inc. today provided an update on its gene therapy program, including progress on the Phase I/II open-label clinical trial assessing the safety and optimal dosing level of BAX 335, an investigational factor IX (FIX) gene therapy treatment for hemophilia B, during a sponsored symposium at the 8th Annual Congress of the European Association for Haemophilia and Allied Disorders (EAHAD) in Helsinki, Finland. [More]
Novavax Commences Enrollment in Phase 1 Clinical Trial of Ebola GP Vaccine

Novavax Commences Enrollment in Phase 1 Clinical Trial of Ebola GP Vaccine

Novavax, Inc., a clinical-stage vaccine company focused on the discovery, development and commercialization of recombinant nanoparticle vaccines and adjuvants, today announced that enrollment has begun in a Phase 1 clinical trial of its Ebola virus glycoprotein (GP) recombinant nanoparticle vaccine candidate adjuvanted with Matrix-M™ (Ebola GP Vaccine) in healthy subjects. [More]
Researchers Demonstrate Biomedical Use of Gold Nanotubes in Mouse Model of Human Cancer

Researchers Demonstrate Biomedical Use of Gold Nanotubes in Mouse Model of Human Cancer

Scientists have shown that gold nanotubes have many applications in fighting cancer: internal nanoprobes for high-resolution imaging; drug delivery vehicles; and agents for destroying cancer cells. [More]
Nanostructured Porous Silicon for Chemotherapy Drug Delivery Behaves Differently in Cancerous Tumors

Nanostructured Porous Silicon for Chemotherapy Drug Delivery Behaves Differently in Cancerous Tumors

A team of Israeli and American researchers have found that silicon nanomaterials used for the localized delivery of chemotherapy drugs behave differently in cancerous tumors than they do in healthy tissues. The findings could help scientists better design such materials to facilitate the controlled and targeted release of the chemotherapy drugs to tumors. [More]