Transdermal Delivery
A MicroArray Patch technology is being developed for the transdermal delivery of large molecule drugs, without the use of injections.
The patch is in a band-aid format, and the surface of the patch is structured with polymer microneedles, from which the drug is delivered. The drugs can be attached to the external surface of the polymer microneedles, integrated into the polymer, or both.
When the patch is applied, the microneedles cross the stratum corneum and penetrate into the epidermis. The microneedles do not penetrate deep enough to enter blood capillaries or nerves, hence the delivery is non-invasive and pain-free.
The drugs for delivery are present in a nanostructured form, facilitating uptake into the body. The microneedles are made of a polymer that is biocompatible and biodegradable. This reduces the risk of trauma to the skin and infection.
The MicroArray Patches have been designed for the delivery of peptides, proteins, hormones, vaccines and skin repair agents. The use of MicroArray Patches will enable a wide range of medications to be effectively delivered to humans in a safe and non-invasive manner.
For further information contact Dr Bob Irving at Nanovic
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