Site Sponsors
  • Oxford Instruments Nanoanalysis - X-Max Large Area Analytical EDS SDD
  • Strem Chemicals - Nanomaterials for R&D
  • Park Systems - Manufacturer of a complete range of AFM solutions

Microfluidics and Particle Sciences Forms Strategic Alliance

Published on June 30, 2009 at 8:36 PM

Microfluidics, a wholly owned subsidiary of Microfluidics International Corporation (OTC Bulletin Board: MFLU - News), and Particle Sciences Inc. (PSI) have formed a strategic alliance to help biopharmaceutical companies leverage the most advanced and reliable nanotechnology and formulation methods available to develop, analyze and commercialize Active Pharmaceutical Ingredients (APIs).

Particle Sciences is a leading Contract Research Organization (CRO) founded in 1991 with a unique specialization in formulation/delivery, analytic services and clinical trial material (CTM) production. With over 35 scientists holding more than 100 patents, a comprehensive formulations laboratory, cGMP production suites and cGMP analytical/bioanalytical capabilities, Particle Sciences has a solid track record of developing commercializable technologies for companies ranging from early venture-backed to large pharma.

According to Robert W. Lee, Ph.D., Vice President of Pharmaceutical Development at Particle Sciences, "We are solution oriented and not married to a specific platform. Our model is to offer our clients a number of state-of-the-art approaches using best-of-breed, reproducible and scalable technologies. Delivery formats range from solid solutions and combination products to particle suspensions and emulsions. For high shear fluid processing, we settled on the Microfluidizer® after a thorough evaluation of the competing alternatives. One area of interest to PSI is adding the Microfluidizer processor to its existing approaches for particle size reduction of poorly water-soluble APIs to the submicron range, which is an increasingly important formulation approach for pharmaceutical API development."

Microfluidizer high shear fluid processors deliver unsurpassed results in uniform and scalable top-down particle size reduction to over 1,100 biopharmaceutical companies worldwide. Combining 25 years of proven processing success with PSI's experience creates a uniquely comprehensive solution portfolio for the Company's pharmaceutical clients. In addition, Microfluidics Reaction Technology (MRT), an innovative technique for bottom-up nanoparticle creation and nanoencapsulation via continuous crystallization and chemical reactions, offers even more possibilities in novel drug development and will also be incorporated into PSI's offerings.

As part of the non-exclusive agreement, Particle Sciences has installed an M-110EH-30 Basic BioPharma Microfluidizer processor ideal for nanoemulsions, nanosuspensions, cell disruption and nanoencapsulation in pilot and production volumes.

"We believe Microfluidizer processors are the undisputed gold standard in the pharmaceutical industry, from the lab to clinical research and production," said Bill Kober, Vice President of Sales, Americas, at Microfluidics. "With several well-known drugs on the market, customers use our processors to reduce particle sizes uniformly, improve bioavailability and target drug delivery. Through this relationship, our users now have access to our technology combined with the scientific ingenuity and experience of Particle Sciences. We are excited to provide a uniquely complete portfolio of solutions for global API research and development."

Tell Us What You Think

Do you have a review, update or anything you would like to add to this news story?

Leave your feedback
Submit