Posted in | Nanoanalysis

Protein and Macromolecule Characterization Solutions on Show in Boston

Published on May 12, 2010 at 10:30 AM

At the Sixth Annual PEGS (17-21 May 2010, Boston MA) Malvern Instruments will exhibit from its comprehensive range of solutions for characterizing proteins and other macromolecules. Today Malvern offers a variety of options, with systems that can be configured to meet the analysis requirements of individual laboratories.

These include the Zetasizer family, which employs dynamic and static light scattering to measure size and molecular weight, and the full range of Viscotek advanced size exclusion chromatography (SEC) systems and detectors for rapid, reliable characterization of both molecular weight and molecular structure.

Malvern's Zetasizer family now includes systems dedicated to the analysis of proteins and other biomolecules. Designed and optimized for maximum sensitivity and minimum sample volume, the Zetasizer Micro V supports improved understanding and management of a wide range of biomolecule applications. These include: optimizing sample and storage conditions; verifying the quaternary structure of protein complexes; identifying thermal characteristics; and assessing protein solubility and sample purity.

When it comes to SEC, Malvern provides a wide choice for chemists seeking either a complete system or an additional detector to enhance an existing set-up. At the heart of the company's chromatography range are Viscotek advanced SEC systems. These include the powerful yet easy to use TDAmax, which can be configured with up to four detectors to deliver maximum information from a single experiment. Light scattering, viscosity, concentration, refractive index and UV detection are all available on the TDAmax. The system delivers information on absolute molecular weight without correction or extrapolation, oligomeric composition and aggregation, protein size and density, conjugate composition and second virial coefficient. OmniSEC software not only offers standard methodologies for instrument control, analysis and customised reporting, it can also deal with specialised applications, such as the analysis of pegylated proteins.

Malvern application experts are available to help configure systems for specific measurement needs, and will be pleased to discuss individual requirements with visitors to the Malvern booth.

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