Microfluidics
(OTCBB: MFLU), the exclusive developer of scalable Microfluidizer® high
shear fluid processors for uniform particle size reduction, robust cell disruption
and bottom-up nanoparticle creation, offers professional Proof of Concept testing
for pharmaceutical, biotechnology, chemical, energy, cosmetic and nutraceutical/food
companies worldwide interested in leveraging the benefits of nanomaterials.
Microfluidics Technology Center engineers, uniquely experienced with a wide
range of nanotechnology applications, experiment with process variables and
recommend formulation changes if necessary in order to optimize product quality
and production efficiency. Lab research most often focuses on nanoemulsions,
liposomes, polymers, suspensions, dispersions, cell disruption, crystallization
and process scaleup. Customers receive a comprehensive report which details
demonstrated results in particle sizing and characteristics relative to specific
goals.
“We had not worked with Microfluidics prior to licensing an injectable
pharmaceutical product that is produced on a Microfluidizer processor located
at a contract manufacturing organization,” said Piyush Patel, Ph.D., Director
of Formulation and Analytical Development at Cephalon, Inc. “The engineers
in the Microfluidics Technology Center were extremely friendly and knowledgeable,
and helped us to understand the effects of varying pressure and interaction
chamber types on our product. By using particle size analyzers in the lab, they
were able to show us results after each pass. This work was very valuable as
it will help us reduce production time and save cost when we prepare to scale
up. In fact, we were so pleased with the performance of the Microfluidizer processor
that we purchased an additional M-110P benchtop unit for our internal research
and development projects.”
Proof of Concept testing is designed to help companies make critical decisions
about sourcing appropriate equipment and developing efficient processes to achieve
aggressive product goals using nanomaterials. An important value-added benefit
is that this effort often jump-starts a more intensive Process Development initiative.
“Our engineers process more than one hundred customer applications each
year,” said Steve Mesite, Microfluidics Technology Center Manager. “This
helps us identify best practices and effective strategies to satisfy customer
requirements across a wide range of applications, from vaccine adjuvants and
coatings to cosmetics and carbon nanotubes. We are fortunate to work with so
many innovative companies because it improves our overall knowledge base which
in turn enhances our ability to find creative solutions that satisfy complex
customer issues.”