NanoInk Releases New Application to Investigate at Single Cell Levels

Published on December 1, 2010 at 1:20 AM

NanoInk's NanoFabrication Systems Division is pleased to announce the launch of a new application for single cell studies that enables micropatterning of proteins and polyethylene glycol (PEG)-based hydrogel at sub cellular scales.

The new application note will be available on NanoInk's Web site in the coming weeks. The NanoFabrication Systems Division will also be presenting a poster and exhibiting at the ASCB (American Society for Cell Biology) 50th Annual Meeting, from Sunday, December 12 through Wednesday, December 15, at the Pennsylvania Convention Center in Philadelphia, Pa.

"The new application demonstrates successful use of the NLP 2000 System to investigate cell response to its microenvironment at single cell levels," said Tom Warwick, general manager, NanoInk's NanoFabrication Systems Division. "We envision that this will enable studies in live single cell arrays, nanotoxicology, developmental biology, tissue engineering, cell physiology, chemotaxis, migration, and mechanotransduction."

Launched in 2009 as a tool for bioscience research, NanoInk's NLP 2000 System is a simple, user-friendly desktop nanolithography platform. The system leverages patented Dip Pen Nanolithography® (DPN®) technology to deposit sub-cellular-scale features of a wide variety of materials with nanoscale registry, all under ambient conditions. With the addition of the new capability to its portfolio of biological research support materials, NanoInk continues to serve as a true partner to the life science community.

NanoInk has successfully demonstrated the patterning of single cells on protein arrays constructed using NanoInk's NLP 2000. Multi-component arrays at sub cellular scales patterned with nanoscale registry have been used to investigate the cellular response at single cell levels. Cell binding areas are constructed using ECM proteins and PEG-based hydrogels are used for targeted delivery of materials to single cells.

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