announces the new Petri dish heater solution for live cell imaging using the
NanoWizard® BioAFM and the CellHesion® product lines.
It has always been a challenge to develop a dimensionally stable thermal capability
for AFM when using plastic components. However, the use of plastics is very
much the standard in cell biology with the benefit of being disposable. JPK
has overcome this with special mechanical adapters and an intelligent drift
compensated design. Plastic and glass-bottomed 35mm diameter Petri dishes from
standard suppliers such as BD, Corning and Wilco can be used.
The new heater system is fully compatible with JPK’s range of NanoWizard®
AFM and CellHesion® systems. This means all the standard imaging and measurement
techniques may be applied at temperatures up to 60°C with 0.1°C precision.
These include fluorescence, transmission illumination, AFM imaging and cell
mechanics study. The system also offers perfusion control employing standard
syringe pumps and gas flow of carbon dioxide possible for long term cell studies.
Glass bottomed dishes are important for high numerical aperture fluorescence
experiments such as confocal laser scanning used in combination with AFM.