recently announced the release of a new super-sensitive system to compliment
their range of instruments for imaging and sizing nanoparticles in liquid suspension.
The system utilizes EMCCD camera technology (Electron Multiplication Charge
Coupled Device), which has improved the sensitivity of the standard NanoSight
systems by a factor of x100.
In practice, this means that the lower limit of detection for a particular
particle type has been improved by a factor of two when compared to the standard
This advance of the new LM10-HS system offers exciting potential in applications
such as the detection of viruses and bacteriophages. The ability to detect very
small, low refractive index viruses (~20nm) and provide absolute virus concentrations
is of paramount importance to those working in vaccine manufacture, phage therapeutics,
virus clearance studies and virus purification. The ability to count virus concentration
had previously only been possible through labor-intensive Electron Microscopy
whereas the NanoSight technique can provide information on virus concentration
in under 1 minute.
A specification sheet for the LM10-HS is available from the NanoSight web site
along with more information about NanoSight and the principles of nanoparticle
tracking analysis. Visit www.nanosight.com.
For more information about NanoSight and how their instrumentation is applied
to applications in both the biological and materials sciences, please visit