NanoBio Corp. announced
today that it is giving an oral presentation at the 2009 Immunotherapeutics
+ Vaccine Summit, which will include preclinical data demonstrating that its
intranasal nanoemulsion adjuvant technology significantly enhances the immune
response to influenza vaccines.
The presentation details are as follows:
- Oral Presentation: W805EC, a Novel Nanoemulsion Adjuvant, Enhances the
Immune Response to Commercial Influenza Vaccines Following Nasal Administration
in Ferrets
Date: Wednesday, August 19 at 10:30 AM
Location: Renaissance Providence Hotel in Providence, Rhode Island
During the presentation, NanoBio will share data demonstrating that intranasal
nanoemulsion-adjuvanted influenza vaccines:
- Elicit strong immune responses after a single vaccination using as low as
1/50th of the antigen dose found in currently marketed vaccines;
- Provide broad cross protection against a range of other influenza A strains
not included in the vaccine administered; and,
- Presented no safety or tolerance concerns in ferrets when administered
nasally.
NanoBio’s nanoemulsion-based, intranasal vaccines have elicited robust
immune responses in animals vaccinated against seasonal and pandemic influenza,
hepatitis B, RSV, HIV, pneumococcal, anthrax, smallpox and other diseases. The
company’s NanoStat™ adjuvant platform technology has demonstrated
numerous potential advantages over traditional vaccines, including: the ability
to generate robust mucosal, systemic and cellular immunity; antigen-sparing
qualities; cross-protection against non-vaccinated strains; ability to adjuvant
multiple antigen types without inducing inflammation; thermally stabilizing
the vaccine; and removing the need for needles.
NanoBio Corp. announced earlier in 2009 that the U.S. Food and Drug Administration
(FDA) approved the company’s Investigational New Drug (IND) application
for the Phase 1 clinical study of NB-1008 for a seasonal influenza vaccine administered
via a nasal dropper. This Phase 1 study is ongoing.
NanoBio® Corp. is a privately held biopharmaceutical company focused on
developing and commercializing dermatological products, anti-infective treatments
and intranasal vaccines derived from its patented NanoStat™ technology
platform. The company’s lead dermatology and anti-infective product candidates
include treatments for herpes labialis (cold sores), onychomycosis (nail fungus),
tinea capitis, acne, molluscum contagiosum, and cystic fibrosis. The company’s
headquarters and laboratory facilities are located in Ann Arbor, Michigan.