Markets, the leading source for international market research and market
data, has announced the addition of Jain PharmaBiotech's new report "Nanobiotechnology
Applications, Markets and Companies" to their offering.
Nanotechnology is the creation and utilization of materials, devices, and systems
through the control of matter on the nanometer-length scale (a nanometer is
one billionth of a meter). Nanobiotechnology, an integration of physical sciences,
molecular engineering, biology, chemistry and biotechnology holds considerable
promise of advances in pharmaceuticals and healthcare. The report starts with
an introduction to various techniques and materials that are relevant to nanobiotechnology.
It includes some of the physical forms of energy such as nanolasers. Some of
the technologies are scaling down such as microfluidics to nanofluidic biochips
and others are constructions from bottom up. Application in life sciences research,
particularly at the cell level sets the stage for role of nanobiotechnology
in healthcare in subsequent chapters.
Some of the earliest applications are in molecular diagnostics. Nanoparticles,
particularly quantum dots, are playing important roles. In vitro diagnostics,
does not have any of the safety concerns associated with the fate of nanoparticles
introduced into the human body. Numerous nanodevices and nanosystems for sequencing
single molecules of DNA are feasible. Various nanodiagnostics that have been
reviewed will improve the sensitivity and extend the present limits of molecular
An increasing use of nanobiotechnology by the pharmaceutical and biotechnology
industries is anticipated. Nanotechnology will be applied at all stages of drug
development from formulations for optimal delivery to diagnostic applications
in clinical trials. Many of the assays based on nanobiotechnology will enable
high-throughput screening. Some of nanostructures such as fullerenes are themselves
drug candidates as they allow precise grafting of active chemical groups in
three-dimensional orientations. The most important pharmaceutical applications
are in drug delivery. Apart from offering a solution to solubility problems,
nanobiotechnology provides and intracellular delivery possibilities. Skin penetration
is improved in transdermal drug delivery. A particularly effective application
is as nonviral gene therapy vectors. Nanotechnology has the potential to provide
controlled release devices with autonomous operation guided by the needs.
Nanomedicine is now within the realm of reality starting with nanodiagnostics
and drug delivery facilitated by nanobiotechnology. Miniature devices such as
nanorobots could carry out integrated diagnosis and therapy by refined and minimally
invasive procedures, nanosurgery, as an alternative to crude surgery. Nanotechnology
will markedly improve the implants and tissue engineering approaches as well.
There is some concern about the safety of nanoparticles introduced in the human
body and released into the environment. Research is underway to address these
issues. As yet there are no FDA directives to regulate nanobiotechnology but
as products are ready to enter market, these are expected to be in place.
Future nanobiotechnology markets are calculated on the basis of the background
markets in the areas of application and the share of this market by new technologies
and state of development at any given year in the future. This is based on a
comprehensive and thorough review of the current status of nanobiotechnology,
research work in progress and anticipated progress. There is definite indication
of large growth of the market but it will be uneven and cannot be plotted as
a steady growth curve. Marketing estimates are given according to areas of application,
technologies and geographical distribution starting with 2008. The largest expansion
is expected between the years 2013 and 2018.
Profiles of 242 companies, out of over 500 involved in this area, are included
in the last chapter along with their 189 collaborations. The report is supplemented
with 39 Tables, 21 figures and 700 references to the literature.