Professor Duncan Graham and his research group at The Centre for Molecular
Nanometrology at the University of Strathclyde has taken delivery of the DPN
5000 nanolithography tool, NanoInk's
latest high precision Dip Pen Nanolithography® (DPN®) system.
The NanoInk DPN 5000 system
Combining high resolution lithography with world class imaging capability,
the new instrument will expand the group's already formidable nanotechnology
toolkit and help Graham move towards in vivo imaging approaches based on functional
nanoparticles and SERS analysis.
Professor Graham is a recognized leader in the field of Surface Enhanced Raman
Spectroscopy (SERS) and an early adopter of DPN technology, driven by the ability
of NanoInk's instrumentation to place nanoscale features directly onto
existing microstructures. The SERS substrate, Klarite®, is an array of gold-coated,
microscale inverted pyramids designed to provide more consistent SERS data.
Graham has demonstrated NanoInk's unique ability to precisely and controllably
deposit materials to the individual pyramids. This combination of DPN and SERS
is one of the few ways of extracting spectroscopic data from nanoscale patterns.
Following this early success with DPN, Graham's lab is applying NanoInk's
instruments to the group's other research interests. For example, they
are now using the NLP 2000 to create large area nanoscale arrays of biomolecules,
nanoparticles and SAM molecules. The team has shown that they can fabricate
highly sensitive protein assays, ultimately leading to the development of new
devices that could revolutionize the detection of cancer biomarkers.
To learn more about DPN, its application and instrumentation platforms, please