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Report Discusses Use of AFMs in Nanoscale Study of Live Cells

Published on January 31, 2012 at 1:17 AM

By Cameron Chai

Research and Markets now offers a new book titled ‘Life at the Nanoscale: Atomic Force Microscopy of Live Cells.’

The nanoscale study of live cells utilizing techniques based on atomic force microscopy (AFM) is a rapidly growing research field. The use of AFMs is increasing over the past few years in order to quantify the forces between cellular interactions, to locate cell surface receptors, to analyze cellular mechanics and to study cell surfaces at superior resolution.

The book includes a comprehensive snapshot of the application of AFMs and other associated scanning probe microscopes for cell surface study, from the fundamentals to the applications. It is useful to people involved in nanobiosciences, biochemistry, biophysics, microbiology, and cell biology. It explains all types of cells, from bacteria to viruses and animal cells to protoplasts. It covers a variety of sophisticated AFM modalities such as recognition imaging, nanoindentation measurements, high-resolution imaging and single-cell and single-molecule force spectroscopy. These measurements based on AFMs helps uncover the structure-function connections of cell membranes and walls. For instance, they can be used for exploring the mechanisms of pathogen–host and cell-drug interactions.

Forward-looking experts are the authors of various chapters of the book that discusses their special areas. Every chapter includes methodologies employed for the preparation and analysis of samples and emphasizes latest examples to exemplify the power of AFM methods in nanomedicine and life sciences.

Source: http://www.researchandmarkets.com

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