Nanoparticle Health Risk Assessment Using the Model 3550 Nanoparticle Surface Area Monitor from TSI Incorporated

Sponsored by TSI IncorporatedApr 21 2008

Topic List

Occupational Health and Safety and Nanoparticles
Model 3550 Nanoparticle Surface Area Monitor
Features and Benefits for the Model 3550 Nanoparticle Surface Area Monitor
Applications for the Model 3550 Nanoparticle Surface Area Monitor

Occupational Health and Safety and Nanoparticles

Occupational health risks associated with using and manufacturing nanoparticles are not clearly understood. Workers may inhale and be exposed to levels that greatly exceed ambient levels. Leading experts contend that surface area, rather than mass, should be measured for nanoparticles, because nanoparticles have far more surface area for the same amount of mass. This increases the chance of reaction with the body. As a result, there is a growing need to study health effects and assess workplace conditions and personal exposure to nanoparticles, based on the measurement of particle surface area.

Model 3550 Nanoparticle Surface Area Monitor

The Model 3550 Nanoparticle Surface Area Monitor from TSI measures the human lung-deposited surface area of particles (reported as µm²/cm³) corresponding to tracheobronchial (TB) and alveolar (A) regions of the lung. The Model 3550 provides a simple and fast solution for measuring the surface area equivalent dose in the lung. The Model 3550 is an important instrument for research in the fields of inhalation toxicology, health effects and epidemiology, and for measuring and monitoring workplace exposure.

Figure 1. The Model 3550 Nanoparticle Surface Monitor from TSI measures lung-deposited surface area of inhaled particles.

Features and Benefits for the Model 3550 Nanoparticle Surface Area Monitor

Features and benefits of the Model 3550 Nanoparticle Surface Area Monitor include:

Selectable measurement modes for tracheobronchial (TB) or alveolar (A) deposition response
Comprehensive software for collection, storage, and display of running-average, time-weighted-average (8-hour), or total deposited surface area
Simple operation, fast set up, and the ability to run continuously for unattended, long-term exposure monitoring
Sensitivity down to 10 nm
Over five decades of concentration, from 0 to 10,000 µm²/cm³ spanning a wide range of exposure dosages
Data rate of one measurement per second detects short periods of high-intensity exposures

Applications for the Model 3550 Nanoparticle Surface Area Monitor

The Model 3550 Nanoparticle Surface Area Monitor is suited to applications such as:

Basic aerosol research
Inhalation toxicology
Industrial hygiene research
Health effects studies
Epidemiology studies
Occupational exposure monitoring

Source: TSI Incorporated
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