PI has provided world class solutions for industry, OEM and research for several decades. PI (Physik Instrumente) L.P., is the U.S. operation of Physik Instrumente (PI) GmbH & Co. KG. The PI family of companies employs more than 350 people world wide. PI is known throughout the high-tech world for its leadership in the design and manufacture of Nanometer-Level Motion Control Products, Piezo Ceramics and NanoActuators, Hexapod 6DOF Positioning Systems and Micro Robots.
M-545 XY Microscope Stage with Ultrasonic Linear Drives
High Stability, Low Profile, High Speed, Direct Position Measurement

The M-545.2U microscope stage with closed-loop ultrasonic piezo motors provides 25 x 25 mm travel range and very high stability
Some key aspects of the device are:
- Integrated Closed-Loop Linear Piezomotor Drives Provide
- Smooth Motion and High Speed to 50 mm/s
- Travel Ranges 25 x 25 mm
- Integrated Linear Encoders with 0.5 μm Resolution
- Compact Design: 30 mm Profile Height
- Mounts Directly to Microscopes
- Self-Locking at Rest, with no Servo Dither
- Compatible with PI Piezo Nanopositioning / Scanning Stages
M-545.2U piezomotor stages are mainly designed for automated positioning applications in microscopy. The form factor of the M-545 is optimized for a low profile height of 30 mm only; the mounting pattern is compatible with many PI piezo nanopositioning stages.
Space Saving Piezomotors
Compared to conventional motorized translation stages, the M-545 provides a lower profile and smaller footprint. The compact PILine® piezoelectric linear motors and linear encoders make both, the lead screw duct and the flanged, bulky stepper motors employed in traditional stages obsolete. In addition, the piezomotors are self-locking at rest and hold the stage in a stable position without generating heat.
Compatibility to PI Nanopositioning and Scanning Stages
A number of standard PI piezo flexure stages (PInano™ family, P-736, etc) can be mounted directly on the M-545 stage. Depending on the application, these highly specialized, ultra- precise nanopositioning systems are available as fast XYZ scanners (for fluorescence microscopy), as vertical Z positioners (3D imaging), or with up to 6 degrees of freedom.

PInano™ XYZ piezo scanner mounted on a M-545.2U Microscope stage. The XYZ piezo nanopositioning stage provides <1 nm resolution and 200x200x200μm scanning range. The high stability and autolocking feature of M-545 provides significant advantages over other microscope stage designs when using fast piezo scanning stages.
Limit and Reference Switches
For the protection of your equipment, non-contact Hall-effect limit and reference switches are installed. The direction-sensing reference switch supports advanced automation applications with high precision.
Advantages of PILine® Micropositioning Systems
The ultrasonic piezoceramic drives used in PILine® micropositioners have a number of advantages over classical drives:
- Higher Acceleration, Speed
- Smooth Motion, no Vibrations
- Small Form Factor
- Self-Locking when Powered Down, no Dither, no Energy Consumption
- No Shafts, Gears or Other Rotating Parts
- Non-Magnetic , Vacuum Compatible Drive Principle



Preliminary Specs
Model |
M-545.2U |
Active axes |
XY |
Travel range |
25 x 25 mm |
Integrated sensor |
Linear encoder |
Sensor resolution |
0.5 μm (no dither at rest) |
Min. incremental motion |
1 μm |
Unidirectional repeatability |
1 μm |
Bidirectional repeatability |
2 μm |
Max. velocity |
50 mm/s |
Load Capacity |
50*N |
Max. push/pull force |
5 N |
Max. lateral force |
4 N |
Motor type |
PILine® U-164 |
Operating voltage |
67 V (RMS)*** |
Electrical power |
10 W / Axis** |
Operating temperature range |
10 to +30 °C |
Material |
Aluminum (black anodized) |
Mass |
3.2 kg |
Cable length |
1.7 m |
Connector |
2 x MDR connector, 14-pin |
Controller/driver |
C-867.260 2-axis Controller/Driver or 2x C-867.160 1-axis Controller/Driver |
* 10 N for max. velocity. ** For drive electronics. *** Piezomotor drive voltage; controller requires 12 VDC

M-545 Manual XY Microscope Stage
For Olympus, Nikon, Leica & Zeiss Microscopes / PI Piezo Stages

M-545 manual XY stage for Olympus, Nikon, Leica & Zeiss microscopes shown with P-545 PInano™ Piezo Stage (not included)

M-545 manual microscopy stages are designde to accommodate the P-545 PInano™ series of XY / XYZ Piezo stages as well as the P-x57, P-5x8, P-56x and P-541/2 series stages.
- For P-545 PInano™ and all P-5xx Nanopositioning Stages
- 25 x 25 mm Travel
- For Olympus™, Nikon™ Leica™ & Zeiss™ Microscopes
- Motor Upgrade with M-229 Linear Drives and C-663 Controllers
Preliminary Specs

M-545.USG Mounting Kit for M-229 Stepper Motor Actuators (requires controllers) Adapter kit for mounting motorized actuators to the M-545 Stage. Order Controllers separate

Compatible with: Nikon Eclipse Ti Series (Ti-S, Ti-U, Ti-E) Olympus IX Series (IX71 and IX81) Leica DMI Series (DMI3000, DMI4000, DMI5000 and DMI6000) Zeiss Axio Observer Series (A1, D1 and Z1)
Model Survey
The M-545 Series of stages is designed for use with inverted microscopes from the leading manufacturers (Nikon, Olympus, Leica and Zeiss). The stages are designed to allow full rotation of the lense turret throughout the Z motion range of The turret.

Compatibility
The M-545 is designed to provide a highly stable mounting platform for the PI nano series of piezo electric nanopositioning stages. The PI nano was designed for microscopy applications and has accessories that facilitate mounting the sample near the bottom surface of the stage and within the focal range of the microscopes.
The M-545 also has mounting holes for a variety of other PI nanopositioning stages.
The following is a list of PI stages that can be used with the M-545:
P-545 |
PInano™ Series XY and XYZ Stages, all versions |
P-736 |
PInano™ Series Z high speed Z scanner Adapter kit P-736.AP1 required |
P-5x7 and P-528 |
PI Multi-Axis Piezo Scanner, all versions |
P-561 and P-562 |
PIMars™ XYZ Piezo System, all versions |
P-541 and P-542 |
PI Low Profile Nanopositioning Stage, all versions |
P-733 |
Compact, High Precision XYZ nanopositioning stage All versions Adapter kit P-733.AP1 required |
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Focal Point Location
PI has designed the P-545 stage to be easily integrated to commercial microscopes through the use of the M-545 stage. M-545 stages are available for Nikon, Olympus, Zeiss and Leica inverted microscopes.These stages mount directly to the microscope base and accept the P-545.3R2 and P-545.2R2 as well as several other PI stages. The M-545 stages can be manually driven through micrometers or using PI’s precision motorized actuators. Contact your PI sales representative for details.
When used in a microscope application, the focal plane for the microscope is located near the bottom of the stage. It is for this reason that the stage has a lower mounting surface. The figure below shows the nominal location of the focal plane. Vertical travel of the objective varies based on the microscope used.
A series of accessories is available from PI to assist with mounting a sample holder to the stage. The P-545.SH1 is available to hold standard 1”x 3” (25mm x 75mm) microscope slides and the P-545.PD1 is offered for holding 35mm Petri Dishes.

M-545k Manual Microscope Stage
For Bread-Board Mount / PI Piezo Stages

Stack of two M-545k manual stages
Some key aspects of the device are:
- For P-545 PInano™ and all P-5xx Nanopositioning Stages
- 25 mm Travel
- Motor Mike Upgrade with M-232 Actuators and C-863 Controllers
- For Bread Board Mount on 1/4-20 -1" Centers
Preliminary Specs

M-545k manual msicroscopy stages are deignde to accommodate the P-545 PInano™ series of XY / XYZ Piezo stages as well as the P-5x7, P-5x8, P-56x and P-541/2 series stages.


Stack of two M-545k manual stages with P-545 PInano™ Piezo Stage (not included)

This information has been sourced, reviewed and adapted from materials provided by PI (Physik Instrumente) LP, Piezo Nano Positioning.
For more information on this source, please visit PI (Physik Instrumente) LP, Piezo Nano Positioning.