How Does an Ultrasonic Processor Work?

The ultrasonic electronic generator converts AC line power to a 20 KHz signal that powers a piezoelectric convertor/transducer. The transducer in turn converts this electrical signal to a mechanical vibration because of the attributes of the internal piezoelectric crystals.

This mechanical vibration is intensified and passed down the length of the probe or horn where the tip expands and contracts longitudinally. The distance travelled by the tip depends on the amplitude chosen by the user via the amplitude control knob.


In liquid, the fast vibration of the tip results in the formation and collapse of microscopic bubbles. This phenomenon is dubbed as cavitation. The breakdown of countless number of cavitation bubbles, releases significant amount of energy in the cavitation field.

Following this, surfaces and objects inside the cavitation field are processed. The diameter of the probe tip controls the amount of sample that can be suitably processed. Diameters of smaller tips i.e. microtip probes provide high intensity sonication; however the energy is directed inside a small, concentrated area. Although larger volumes are processed by larger tip diameters, they deliver low intensity sonication.


The options of a generator and horns or probes correspond to several factors, such as viscosity, volume, etc. of a specific application. A Misonix Sonicator product specialist can help in choosing the right generator and horn for particular applications.

About Qsonica

Qsonica designs, develops and manufactures the world's most technologically advanced ultrasonic liquid processors. Our 40 years of experience in a wide range of industries has enabled us to develop a full line of equipment and accessories to provide solutions for the following applications:

  • Cell Disruption
  • Nanoparticle Dispersion
  • Creating Emulsions
  • Shearing DNA
  • ChIP Assay
  • Homogenization

This information has been sourced, reviewed and adapted from materials provided by Qsonica - Ultrasonic Liquid Processors.

For more information on this source, please visit Qsonica - Ultrasonic Liquid Processors.


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