NexION® 350 ICP-MS Spectrometers from PerkinElmer

PerkinElmer offers the new NexION® 350 ICP-MS spectrometer that enables users to quickly and accurately measure and characterize nanoparticles.

The system has 10 times faster data acquisition speed compared to other ICP-MS available on the market.

The NexION® 350 ICP-MS provides increased productivity and uptime through a range of exclusive features designed to improve signal stability.

It uses PerkinElmer’s Syngistix™ workflow-based software, which features an intuitive interface and novel automatic method setup tools for rapid implementation.

In addition, the optional Nano Application Module in the software can be integrated with the spectrometer for exceptional detection and characterization of nanomaterials.

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An Overview of the NexION® 350 ICP-MS Single Particle Analyzer

The NexION® 350 ICP-MS combines a variety of technical innovations that enhance signal stability, reduce maintenance needs and downtime, lower background and interferences, and produce better results.

It is available in four different models to suit specific application requirements.

Key Features

The main features of the NexION® 350 ICP-MS spectrometers are as follows:

  • High speed data acquisition
  • Simultaneous dual mode detector
  • Includes large, easily accessible area for sample introduction
  • Low liquid uptake nebulizer
  • Free-running RF plasma generator
  • Universal Cell Technology with three modes of operation: Standard, Collision or Reaction
  • Custom-designed, four-stage vacuum system
  • Full color plasma view
  • Fully automatic X, Y, Z torch positioning
  • Triple Cone Interface creates the most tightly focused ion beam in the industry and reduces sample build-up on internal components
  • Quadrupole Ion Deflector changes positively charged ions 90° into the Universal Cell and filters off neutrals
  • Unique steel alloy Quadrupole for unparalleled stability
  • Requires no extraction lenses for cleaning
  • Simple operation through PerkinElmer’s Syngistix™ workflow-based software
  • Benchtop design with no rear connections

Example Applications

Listed below are just a few of the many applications which the NexION® 350 ICP-MS can be used for:

Using Single Particle ICP-MS to Characterize Silver Nanoparticles in Dietary Supplements

Silver nanoparticles (AgNPs) are the most widely used nanoparticles in consumer products, thanks to their antimicrobial properties. The small size and high surface area of AgNPs increase their efficacy as an antimicrobial through high reaction rates.

Using SP-ICP-MS to Analyze Nanoparticles in Biological Tissues

SP-ICP-MS is the ideal technique for ENP analysis due to its ability to provide data regarding particle size, count, and mass distributions at significant concentrations and can determine all three nano-specific parameters from a single sample.

Understanding Single Particle ICP-MS Analysis

Today, nanoparticles are being utilized in a wide variety of products and materials, such as clothing, coatings, fuel additives, etc., thus characterizing nanoparticles is very important.

Characterizing Nanoparticle Element Oxide Slurries in Chemical-Mechanical Planarization Using Single Particle ICP-MS

In the semiconductor and nanoelectronics fabrication industry, the chemical-mechanical planarization (CMP) process is used for smoothing semiconductor surfaces for photolithography using chemical and mechanical forces.

Nowadays, CMP slurries containing nanoparticles are used for miniaturization of electronic devices and improvement of productivity.

Measuring the Exposure and Effects of Silver Nanoparticles in Surface Water Using ICP-MS

Over the last 10 years, there has been a significant increase in the production and application of engineered nanomaterials which has increased the possibility of release into surroundings.


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