Testing of Magnetic Nanoparticles and Fluids at Stable Radio Frequencies – magneTherm

The magneTherm™ system from nanoTherics is a completely unique, competitively priced device, which facilitates testing of nanoparticle hyperthermia and magnetic fluids.

The device functions at a broad range of frequencies that are user configurable in a single system and it does not require any hidden extras.

Although the availability of magnetic nanoparticles and their use is considerably increasing, until now there have been no systems available on the market that are capable of hyperthermia testing of these particles in particular applications at a range of appropriate field strengths and frequencies.

nanoTherics has acknowledged the challenge in sourcing off-the-shelf device which matches this requirement but still facilitates for adaptability in choice of both low and high frequencies used. This device has been built particularly for this purpose, functioning at a broad range of frequencies (*50 kHz to 1 MHz) with field strengths up to 20 kA/m (25 mT).

As the heating capacity of the magnetic nanoparticles would change depending on shape, size and material characteristics, it is important to be able to estimate heating capacity on a wider range of frequencies.

Ten Standard Frequencies

Frequency Maximum Field Strength (mT) Maximum Field Strength (Oersted) Maximum Field Strength (kA/m)
110 25 250 19.9
168 17 170 13.5
176 23 230 18.3
262 23 230 18.3
335 17 170 13.5
474 11 110 8.7
523 20 200 15.9
633 9 90 7.2
739 16 160 12.7
987 12 120 9.5

It is possible to reduce all the field strengths from maximum to zero in mT steps, if needed by the operator.

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Key Features

  • Wide sample aperture facilitates in-vivo, calorimetric, materials and in-vitro experiments in a single area
  • Requires only recirculating water bath or a tap for cooling: maintains room temperature
  • Low and high frequency from 100 kHz to 1000 kHz offers user adaptability within a single system
  • Easy to use bench-top size reduces footprint and offers portability
  • Horizontal and vertical sample enclosure positioning allows the device to be used with animal models and nanoparticle samples
  • Offers user adaptability, which enables users to use the device for in vivo mouse studies

Proven Results

The proven results include heating profile data of 0.6ml of Fe2O3 1 mol/L sample in dH2O compared over 0. 6ml of dH2O control sample at 110 kHz, 25 mT. Users can notice the rise of iron oxide temperature within five minutes when it is exposed to 25 mT alternating magnetic field with 110 kHz frequency subjected through magneTherm. This data was provided by Dr. Christine Menager from University of Paris.

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