MFP-3D-BIO AFM for Bioscience Research

The Asylum Research MFP-3D-BIO is the industry standard for combining AFM and optical microscopy in bioscience studies. It is the only bio-AFM that does not sacrifice AFM imaging resolution, force measurement effectiveness, or application functionality while incorporating a seamlessly wide range of optical methods. This, combined with unrivaled assistance from Asylum experts, makes it the perfect and most effective AFM for advancing research.

  • Performance leadership in force spectroscopy and force mechanics
  • Matchless versatility to fulfill the varied requirements of multiple users
  • Uncompromised AFM performance incorporated with optical microscopy
  • Unrivaled support from bio-AFM professionals to get the results users need
  • Easy, high-resolution imaging in liquid on soft biological samples

Features and Benefits

Uncompromised AFM Performance Integrated with Optical Microscopy

  • High-quality objective allows for easy viewing of opaque samples, laser alignment, and can be used as a condenser for bright field or phase contrast illumination on transparent samples
  • Live-time optical navigation
  • Brighten or observe with built-in top-down optics
  • Great real-time and offline rendering options including optical and AFM image overlays
  • Supports several optical methods like Brightfield, Phase Contrast, Epifluorescence, Confocal Microscopy, TIRF, FRET, FCS, FRAP, Ion Indicators (for example Ca2+ response)

Simple, High-Resolution Imaging in Liquid on Soft Biological Samples

  • Controlled gas or liquid environment choices that are easy, safe, and effective
  • Several environmental accessories for temperature control and simplifying imaging in liquid
  • ModeMaster™ spontaneously configures software for the selected mode
  • GetStarted™ spontaneously sets optimal parameters for tapping mode imaging
  • SmartStart™ spontaneously detects and configures system components to get results quickly
  • GetReal™ spontaneously calibrates the cantilever spring constant and sensitivity

Performance Leadership in Force Spectroscopy and Force Mechanics

  • Thermally-limited force resolution (<8 pm deflection noise typical, <20 pm guaranteed)
  • Select between open-loop force curves with censored Z for the ultimate in low noise performance or closed-loop Z for the most precise velocity control.
  • Large Z range (15 µm standard, 40 µm extended Z option) includes severe applications such as cell-cell and cell-substrate adhesion measurements.
  • Force Mapping measures force-distance curves at a grid of points with the automatic fitting of indentation models for an approximation of elastic modulus and automated adhesion/rupture force analysis.

Unmatched Versatility to Satisfy the Diverse Needs of Multiple Users

  • Unmatched range of nano electrical and electromechanical characterization modes
  • Exclusive accessories for applying external forces to an extensive range of samples
  • Full suite of nanomechanical characterization modes available for measuring viscoelastic properties (storage/elastic modulus and loss modulus)

Unrivaled Support from Bio-AFM Experts to Get the Results Needed

  • No-charge technical support and expert applications support for life
  • Comprehensive warranty and repair costs are the lowest in the industry
  • Comprises a standard one-year complete warranty

Operating Modes

Included Operating Modes

  • Contact mode
  • Dual AC™
  • Dual AC Resonance Tracking (DART)
  • Electrostatic Force Microscopy (EFM)
  • Frequency modulation
  • Force modulation
  • Force curves
  • Force Mapping Mode (force volume)
  • Kelvin Probe Force Microscopy (KPFM)
  • Loss tangent imaging
  • Lateral Force Mode (LFM)
  • Magnetic Force Microscopy (MFM)
  • Nanomanipulation
  • Nanolithography
  • Piezoresponse Force Microscopy (PFM)
  • Phase imaging
  • Switching spectroscopy PFM
  • Tapping mode with digital Q control
  • Tapping mode (AC mode)
  • Vector PFM

Optional Operating Modes

  • AM-FM Viscoelastic Mapping Mode
  • Conductive AFM (CAFM) with ORCAand Eclipse Mode
  • Contact Resonance Viscoelastic Mapping Mode
  • High voltage PFM
  • Scanning Tunneling Microscopy (STM)
  • Scanning Thermal Microscopy (SThM)
  • Scanning Microwave Impedance Microscopy (sMIM)

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