MFP-3D-BIO AFM for Bioscience Research

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The Asylum Research MFP-3D-BIO is the industry standard for combining AFM and optical microscopy in bioscience studies. It is the only bio-AFM that does not sacrifice AFM imaging resolution, force measurement effectiveness, or application functionality while incorporating a seamlessly wide range of optical methods. This, combined with unrivaled assistance from Asylum experts, makes it the perfect and most effective AFM for advancing research.

Performance leadership in force spectroscopy and force mechanics
Matchless versatility to fulfill the varied requirements of multiple users
Uncompromised AFM performance incorporated with optical microscopy
Unrivaled support from bio-AFM professionals to get the results users need
Easy, high-resolution imaging in liquid on soft biological samples

Features and Benefits

Uncompromised AFM Performance Integrated with Optical Microscopy

High-quality objective allows for easy viewing of opaque samples, laser alignment, and can be used as a condenser for bright field or phase contrast illumination on transparent samples
Live-time optical navigation
Brighten or observe with built-in top-down optics
Great real-time and offline rendering options including optical and AFM image overlays
Supports several optical methods like Brightfield, Phase Contrast, Epifluorescence, Confocal Microscopy, TIRF, FRET, FCS, FRAP, Ion Indicators (for example Ca2+ response)

Simple, High-Resolution Imaging in Liquid on Soft Biological Samples

Controlled gas or liquid environment choices that are easy, safe, and effective
Several environmental accessories for temperature control and simplifying imaging in liquid
ModeMaster™ spontaneously configures software for the selected mode
GetStarted™ spontaneously sets optimal parameters for tapping mode imaging
SmartStart™ spontaneously detects and configures system components to get results quickly
GetReal™ spontaneously calibrates the cantilever spring constant and sensitivity

Performance Leadership in Force Spectroscopy and Force Mechanics

Thermally-limited force resolution (<8 pm deflection noise typical, <20 pm guaranteed)
Select between open-loop force curves with censored Z for the ultimate in low noise performance or closed-loop Z for the most precise velocity control.
Large Z range (15 µm standard, 40 µm extended Z option) includes severe applications such as cell-cell and cell-substrate adhesion measurements.
Force Mapping measures force-distance curves at a grid of points with the automatic fitting of indentation models for an approximation of elastic modulus and automated adhesion/rupture force analysis.

Unmatched Versatility to Satisfy the Diverse Needs of Multiple Users

Unmatched range of nano electrical and electromechanical characterization modes
Exclusive accessories for applying external forces to an extensive range of samples
Full suite of nanomechanical characterization modes available for measuring viscoelastic properties (storage/elastic modulus and loss modulus)