Alnis is a drug development company with a potent, enabling therapeutic platform to treat cancer as well as infectious and inflammatory diseases. Alnis has engineered nanoscopic hydrogels, or NanoGels, comprised of polymers, bioactives, and targeting molecules. These NanoGels are intended to selectively target pathological tissues, treat the disease, and afterwards simply disintegrate, returning to the individual components from which they were formed. Throughout this process, the NanoGels are designed to provide the patient with a lower systemic exposure to the toxic effects of bioactive components than previously possible. Additionally, nanogels are designed to improve potency. This combination of better safety and higher efficacy produces a large increase in therapeutic index.
Proprietary NanoGels to treat cancer and infectious diseases are actively under development at Alnis. The Company's first target indications are cancer Ð renal, breast, and liver, in particular, where patients are poorly served by current therapeutics. Solid tumors such as these possess a leaky vasculature that allows chemotherapeutic-rich NanoGels to exit the bloodstream and enter the tumor. The blood vessels of healthy tissues are not leaky, so these particles cannot as easily enter healthy tissue.
Professor Andre Nel
In this interview, AZoNano speaks with Professor Andre Nel about his involvement in innovative research describing the development of a 'glass bubble' nanocarrier that could help drug formulations access pancreatic cancer cells.
Jingang Li, Ph.D.
In this interview, AZoNano speaks with Jingang Li from the University of California, Berkley, who offers an introduction to the Nobel Prize-winning technology, Optical Tweezers.
Steve Kosier, Ph.D.
In this interview, we speak with SkyWater Technology about the current state of the semiconductor industry, how nanotechnology has helped to shape this sector, and their new partnership which aims to increase the accessibility of semiconductor chips for start-ups and research groups across the Unite
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