Automate Repeated Syntheses with NMReady-flow

The NMReady-flow kit allows easy inter-conversion of any Nanalysis 60e or 60PRO benchtop spectrometer into an online NMR detector either in combination with other analytical methods or as a standalone tool.

NMReady-flow allows users to:

  • Automate repeated syntheses
  • Understand and improve chemical reactions in real time
  • Enhance reaction yield and safety
  • Integrate the NMReady, a centralized laboratory system

Why NMR Spectroscopy?

  • NMR spectroscopy is a linear, non-destructive method
  • Chemically specific information regarding all molecular species present in solution at a given time, including structural connectivity
  • Non-targeted analysis
  • Inherently quantitative with little or no calibration

Why Benchtop NMR?

  • Benchtop NMR offers considerably enhanced economics
  • Compact, low maintenance tool can be positioned at the point of need for smaller sample loop
  • Lower capital and operating costs
  • Automated acquisition and shimming routines
  • No special power or safety requirements
  • No trained maintenance staff needed

Data Acquisition

  • The Flow cell is easy-to-install and can be sealed from the environment
  • Small sample loop reduces lag
  • Can monitor a range of nuclei (For example, 11B, 1H, 19F, 31P)
  • Improve reactions, identify byproducts, or monitor the extent of reaction
  • Data processing can be automated
  • Experiments can be started on-board, via NMReady-CONNECT or third-party software

Technical Specifications

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Configuration: Bottom-to-top
Material: Mixed medium glass / PTFE
Internal diameter: 4.8 mm
Outer diameter: 5.0 mm
Flow mode: Continuous or stopped flow
Flow rate: <4.0 mL per minute


NMReady Flow Setup

Video Credit: Nanalysis Corp.

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