The MFP-3D-BIO from Asylum Research is the industry standard for combining AFM and optical microscopy in bioscience research. It is the only bio-AFM that does not compromise on AFM imaging resolution, force measurement performance, or application versatility while seamlessly integrating with a full range of optical techniques.
This, combined with unparalleled support from Asylum specialists, makes it the finest, most productive AFM for furthering the study.
Device Overview
- Unrivaled AFM performance combined with optical microscopy
- Performance leadership in force spectroscopy and force mechanics
- Simple, high-resolution imaging in liquid on delicate biological samples
- Unequaled flexibility to meet the different needs of multiple users
- Unmatched support from bio-AFM experts to get the required results
Features and Benefits
Uncompromised AFM Performance Integrated With Optical Microscopy
- Real-time optical navigation
- Illuminate or view with in-built top-down optics
- Robust real-time and offline rendering options, including optical and AFM image overlays
- High-quality objective enables effortless viewing of opaque samples and laser alignment, and can be utilized as a condenser for brightfield or phase contrast illumination on transparent samples
- Various optical techniques like Brightfield, Epifluorescence, Phase Contrast, Confocal Microscopy, FRET, TIRF, FRAP, FCS, and Ion Indicators (Ca2+ response) are supported
Simple, High-Resolution Imaging in Liquid on Soft Biological Samples
- Various environmental attachments for temperature control and improving imaging in liquid
- Simple, safe, and effective controlled gas or liquid environment options
- ModeMaster™ configures software for the selected mode
- SmartStart™ automatically identifies and configures system components to obtain results rapidly
- GetStarted™ automatically sets optimal parameters for tapping mode imaging
- GetReal™ calibrates the cantilever spring constant and sensitivity
Performance Leadership in Force Spectroscopy and Force Mechanics
- Large Z range (15 µm standard, 40 µm extended Z option) enables demanding applications like cell-cell and cell-substrate adhesion measurements
- Thermally-limited force resolution (<8 pm deflection noise typical, <20 pm assured)
- Force Mapping measures force-distance curves at a grid of points with the automated fitting of indentation models for estimation of elastic modulus and automated adhesion/rupture force analysis
- Select between open-loop force curves with sensored Z for the best in low noise performance or closed-loop Z for the most precise velocity control
Unmatched Versatility to Satisfy the Diverse Needs of Multiple Users
- A comprehensive suite of nanomechanical characterization modes for evaluating viscoelastic properties (storage/elastic modulus and loss modulus) is provided
- An unparalleled range of nanoelectrical and electromechanical characterization modes
- Distinct accessories for applying external forces to a broad range of samples
Unrivaled Support From Bio-AFM Experts To Get the Results
- A standard one-year comprehensive warranty
- Life-long free technical support and expert applications assistance
- Industry-leading prolonged warranty and repair costs