At Analytica 2010 (23-26 March 2010, Munich, Germany) Malvern
Instruments will focus on its range of analytical instrumentation for life
science applications, with an emphasis on the company's comprehensive solutions
for characterizing proteins and other macromolecules.
Today Malvern offers a variety of options, with a range of systems that can
be configured to meet the analysis requirements of individual laboratories.
These include the Zetasizer family, which employs dynamic and static light scattering
to measure size and molecular weight, and the full range of Viscotek advanced
gel permeation / size exclusion chromatography (GPC/SEC) systems and detectors
for rapid, reliable characterization of both molecular weight and molecular
In addition to the established and widely used Zetasizer Nano system, Malvern's
Zetasizer family now includes a system dedicated to the analysis of proteins
and other biomolecules. Designed and optimised for maximum sensitivity and minimum
sample volume, the Zetasizer Micro V is a dedicated system that supports improved
understanding and management of a wide range of biomolecule applications. These
include: optimising sample and storage conditions; verifying the quaternary
structure of protein complexes; identifying thermal characteristics; and assessing
protein solubility and sample purity.
When it comes to GPC/SEC, Malvern provides a wide choice for chemists seeking
either a complete system or an additional detector to enhance an existing set-up.
At the heart of the company's chromatography range are Viscotek advanced
GPC/SEC systems. These include the powerful yet easy to use TDAmax, which can
be configured with up to four detectors to deliver maximum information from
a single experiment. Light scattering, viscosity, concentration, refractive
index and UV detection are all available on the TDAmax. The system delivers
information on absolute molecular weight without correction or extrapolation,
oligomeric composition and aggregation, protein size and density, conjugate
composition and second virial coefficient. OmniSEC software not only offers
standard methodologies for instrument control, analysis and customised reporting,
it can also deal with specialised applications, such as the analysis of pegylated
Malvern application experts are always available to help configure systems
for specific measurement needs, and will be pleased to discuss individual requirements
with visitors to the Malvern stand A1.320 at Analytica. www.malvern.com/analytica2010