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bpifrance Grants Nanobiotix €9 Million to Advance NBTXR3 for Liver Cancer

Published on July 5, 2013 at 4:46 AM

NANOBIOTIX, a clinical-stage nanomedicine company pioneering novel approaches for the local treatment of cancer, announces today it has secured c.€9 million in funding from bpifrance (formerly OSEO) of which €2.8 million is directly attributable to the Company.

This grant, awarded through bpifrance’s Strategic Industrial Innovation (ISI) program, will accelerate the clinical and industrial development of the Company’s lead product NBTXR3 in a new indication, liver cancer (hepatocellular carcinoma). Liver cancer is a major health problem that causes one of the greatest number of deaths each year worldwide, c.695,000 deaths per annum.

This grant supports the launch of NICE (Nano Innovation for CancEr), the first consortium of nanomedicine stakeholders in France focused on characterization and industrialization aspects. The consortium has been accredited by the Medicen Paris Region, a competitive cluster for innovative therapies in Ile-de-France.

Consisting of five public and private partners, the NICE consortium includes partners with in depth expertise in the field of nanomedicine. Its mission is to build a platform to accelerate the development and industrialization of nanomedicine in France by capitalizing on the strong and complementary expertise of each partner.

Nanobiotix’s lead product NBTXR3, based on NanoXray, is currently under clinical development for advanced soft tissue sarcoma and has received authorization from the French Medicine Agency, ANSM, to start a second clinical trial in patients with locally advanced cancers of the oral cavity or oropharynx (head and neck cancer). NBTXR3 will benefit fully from this platform of expertise and funding received from bpifrance by being able to accelerate its clinical development. The purpose of this project is the start of a new Phase I clinical study with NBTXR3 in patients with primary liver cancer.

In addition to Nanobiotix, the consortium includes BioAlliance Pharma, leader of the consortium which is developing Livatag®, a doxorubicin nanoparticle currently in Phase III clinical trial for treatment of primary liver cancer; CEA-Leti, the developer of cancer-detecting nanoparticles based on Leti’s Lipidots® platform; DBI, a company specialized in the production of nanomedicine pharmaceutical products and the Institut Galien Paris Sud (University Paris Sud/CNRS), which has an academic-excellence team specialized in nanoparticle research.

Source: http://www.nanobiotix.com/

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