Posted in | News | Nanomedicine

Advanced Research Fellowship May Lead To DNA Being Used as a Building Block For Self Assembling Nanostructures

Dr Glenn Burley, from the University of Leicester, has been awarded one of only 8 coveted Advanced Research Fellowships in Chemistry worth £922 K, given annually by the Engineering and Physical Sciences Research Council (EPSRC).

The highly prestigious award will allow the Leicester research to use DNA, the molecule of inheritance, to help build tiny structures for use in technology processes and medicine.

Dr Burley said: “Astonishingly, strands of DNA can be programmed to self assemble into complex arrangements.

“DNA scaffolds made in this way could be used to hold molecule size electronic devices or be used to build materials with precise configurations.

‘By altering parts of their structure from one conformation to another, DNA can even be used as a machine’ says Dr Burley. ‘It’s amazing that nature’s hard drive can be so versatile. The real challenge now is to harness the potential of DNA in nanotechnology. If we can achieve this, then it will enable us to build devices much smaller than we can be achieved with today’s technology.”

Dr Burley said DNA nanotechnology combines chemistry, biochemistry and physics: “In the near future devices will contain DNA components alongside traditional electronic components. Other benefits of this technology include reduced cost of device construction and the potential for use in the early diagnosis of genetic diseases.

“We could use the technology to devise new methods of constructing DNA chips that can be used to predict whether a person will be predisposed to a particular disease.

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