Posted in | News | Nanomedicine

Strategic Partnership Focuses on Targeted Drug Delivery

Calvert Research, LLC (a Calvert Holdings, Inc. company) and Auburn University announced today a joint research project entitled, Targeted Drug Delivery. Undertaken through Auburn University College of Veterinary Medicine's Department of Pathobiology, the six-month study is under the direction of Dr. Valery Petrenko. Dr. Lonnie Bookbinder, west coast regional director, is coordinating the research on behalf of Calvert Research LLC.

The study will center on the hypothesis that targeting siRNA-containing pharmaceutical nanocarriers, such as liposomes, with breast tumor-specific phage proteins may significantly enhance their anti-cancer activity. "This particular study was selected after an extensive nationwide effort to research numerous potential delivery technologies," stated Dr. Bookbinder. He continued by adding: "Calvert Research LLC looks forward to advancing science through this partnership with Auburn University and Dr. Petrenko."

"I am very pleased to collaborate with Calvert," Dr. Petrenko said. "Their experts first recognized that the merging of phage nanobiotechnology developed at Auburn with genomics can contribute vigorously to different areas of medicine, specifically in the area of targeted cancer therapy. I believe the new concept of phage-driven drug-delivery, which we explore in our partnership program, will demonstrate its power and vitality in the near future."

"This is an exciting opportunity for Auburn to contribute to the advancement of drug delivery technologies. This partnership with Calvert Research represents another example of how our college is working with Auburn's Office of Technology Transfer to market our faculty's discoveries," said Dr. Timothy R. Boosinger, dean.

"The Auburn project fits our plans to invest in novel therapeutic approaches that will advance clinical development of new drug compounds. We share the belief that future pharmaceuticals and biologicals will have targeted delivery," explained Russ McLauchlan, CEO of Calvert Holdings Inc. "Our alliance with Auburn University gives us a position in this growing field."

Scheduled to conclude in April 2009, the study's results will be published by Auburn University.

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