AB SCIEX and Advion BioSystems have jointly unveiled the LESA Clarity for AB’s Mass Spec Systems.
The solution forms part of an existing collaboration between the two companies and Oak Ridge National Laboratory (ORNL), providing user friendliness and more capabilities to the Liquid Extraction Surface Analysis (LESA) platform that was been released in March 2010.
Research teams will find the solution ideal in the development of drugs, forensic tools, enhanced biofuels and food safety. It will also help develop technologies that can be used in interior security. It delivers added functions that enhance performance levels of AB’s mass spectrometry systems. A rapid high resolution camera system has also been integrated that enhances the images of the solvent droplet communication with the surface, making it easy to develop new methods and enable fine tuning. It incorporates the Analyst, an AB software platform, and Chipsoft, which is a TriVersa NanoMate software that enables research teams to operate the system using one computer with a sample batch queue. These features make it possible for all data to be stored in a single file.
A use-and-throw pipette tip is placed above a predetermined spot on the sample. A droplet of solvent is brought into contact with the surface of a planar prototype to obtain the analytes. The analyte-laden droplet is sucked back into the pipette tip and delivered behind the 400-nozzle ESI Chip with the nanoESI’s spray times to enable in-depth MS analysis. The sampling sites are integrated into a batch queue to be used for future automatic analysis. The system also delivers data to DESI, DART and MALDI.
LESA was created at ORNL to incorporate benefits of nanoelectrospray and mass spectrometry (nanoESI/MS) into surface analysis and make surface sampling automatic to enable rapid analysis. It delivers direct mass spectrometric analysis and does not require sample preparation in multiple formats such as tissue and organs, Thin Layer Chromatography (TLC) and MALDI plates. The system is applicable with AB’s mass spectrometers.
Source: http://www.absciex.com