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Microfluidics is a new technology platform that deals with the behavior, precise control and manipulation of fluids that are geometrically constrained to a small, typically sub-millimeter, scale. Microfluidic and nanofluidic systems analyse by controlling the flow of liquids or gases through a series of tiny channels and valves, thereby sorting them, much as a computer circuit sorts data through wires and logic gates. Microfluidic channels, often etched into silicon, can be less than 100 nm wide. This allows them to handle biological materials such as DNA, proteins or cells in minute quantities - usually nano-liters or pico-liters (1000 times smaller than a nano-liter). Microfluidics not only enable very precise analysis, they also open up the potential for manipulation of living matter by mixing, separating and handling different components at the nanoscale.
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Equipment
Micropumps, especially those based on electroosmotic flow (EOF), are essential components in microfluidic lab-on-a-chip devices, as they contain no moving parts and are relatively easy to integrate in microfluidic circuits during fabrication.
The Mitos Linear In-line Interface works in conjunction with two Edge connectors, providing inline sealing between two sets of tubing. There are three sizes of in-line connector to fit the 4-way (part number 3000024), 8-way (3000102) and 12-way (3000067) Edge connectors. This connector provides a fast and reliable means of connection between two sets of 1.6mm (1/16inch) O.D. tubing.
The Droplet Generator Chip is designed for generating droplets made up of one, two or three reagents. Applications include monodispersed droplet formation, emulsion formation and Janus particle formation. It is supplied with a location pin allowing connection to the Mitos Circular Connector.
The new Model M-710 from Microfluidics is a 100 HP high shear fluid processor capable of producing nominal flow rates anywhere from 2.3 gpm (8.7 l/m) at 40,000 psi (2760 bar) to 15 GPM (57 l/m) at 5,000 psi (345 bar). The dual synchronous intensifier pumping system develops high pressure through the patented fixed geometry interaction chambers. This action creates shear forces that reduce particles and droplets to submicron sizes with narrow and uniform distribution, usually in a single pass.
The Mitos Resealable Chip Holder is used in combination with microfluidic chips that can be opened and resealed. The chip base layer is loaded into the holder first followed by the gasket and then the chip top layer. The holder clamps the layers together and provides eight fluidic and eight electrical connections to the chip.
The Mitos P-Pump (Part No. 3200016) features an innovative pumping technology providing stable and pulseless flow even at very low flow rates. Operating over a wide pressure range of 0 – 10bar, the Mitos P-Pump offers a flexible solution for microfluidic systems operating from nl/min to ml/min and is suitable for use with viscous liquids.
The Labtrix® system is a fully automated, standardized, "plug and play" platform for laboratory bases reaction screening, optimization and kinetic data determinations using flow chemistry. Labtrix® can be used to perform synthesis at temperatures ranging from -15°C to + 195°C and at pressures of up to 25 bar. Labtrix® can be used to eveluate many reaction parameter in a short period of time, employing very little raw material.
Fluidic Connect is an affordable microfluidic connection platform enabling user-friendly interconnections between the microfluidic chip and peripheral equipment. Fluidic Connect facilitates to create your own lab-on-a-chip set-up. The unique design of the chip holder enables to work safely under high pressure (up to 100 bar / 1450 psi) with a very low (near-zero) dead volume. The material used is chemically inert and mechanically robust.
Dolomite, a world leader in the design and manufacture of microfluidic devices, has introduced the Micro Droplet Systems which enable rapid advances in droplet microfluidics allowing users to produce more than 10,000 monodispersed droplets per second. The Micro Droplet Systems are built around Dolomite’s industry leading microfluidic products and benefit a broad range of applications including the production of monodispersed emulsions or beads
Designed for applications such as droplet generation, reagent dispensing, cell manipulation, microreactions and any application where precise control over fluid flow is required, the Mitos Syringe Pump XS removes pulsation through advanced drive electronics to provide an exceptionally smooth flow.
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