Editorial Feature

Environmentally Friendly Nanoparticle Synthesis

Image Credits: Kichigin/shutterstock.com

Nanotechnology is a rapidly developing science and a number of methods are now available for producing nanoparticles. However, some of these methods employ high energy requirements, low material conversions and the use of hazardous chemicals. Hence, there is a growing need to develop eco-friendly nanoparticle synthesis methods.

Biosynthetic methods such as those that employ plant extracts or microorganisms have emerged as viable alternatives to physical and chemical synthetic procedures.

Nanoparticle Synthesis Using Fungi

Fungi are ideal for synthesizing metal nanoparticles compared with other organisms due to the proteins on their cell surface.

The most common method of intracellular biosynthesis is the production of metal nanoparticles by reducing reductase enzymes present in the cell wall of the fungal cells.

Synthesis of gold nanoparticles has been investigated using Aspergillus, Neurospora, Fusarium and Verticillium species.

Fungus Trichoderma viride has been used to synthesize polydispersed silver nanoparticles of sizes ranging from 5 to 40 nm at near room temperatures. An important finding in this research was that the anti-bacterial activities of substances produced by these fungi were significantly enhanced with the production of silver nanoparticles.

Nanoparticle Synthesis Using Bacteria

Actinomycetes and prokaryotic bacteria have been widely used for the synthesis of metal nanoparticles. One of the main reasons for using bacteria is their relative ease of manipulation.

Researchers have demonstrated an extracellular synthesis of well-dispersed gold nanoparticles using prokaryotic microorganisms such as Thermomonospora and Brevibacterium species. It was also reported that TiO2 nanoparticles can also be synthesized using Sachharomyces and Lactobacillus species at room temperature.

Recently researchers carried out vivo biosynthesis of metal nanoparticles using recombinant Escherichia coli (E. coli). The co-expression of metal binding proteins in recombinant E. coli cells resulted in the generation of fine-ordered nanoparticles through an enhanced attachment of diverse metal elements.

Nanoparticle Synthesis Using Yeasts

Yeasts are eukaryotic microorganisms that belong to the family of fungi, with more than 1500 species.

Several studies indicate the efficiency of yeasts in nanoparticle preparation. For instance, silver-tolerant yeast strain MKY3 was used to demonstrate the extra-cellular formation of silver nanoparticles. Yarrowia lipolytica was reported to be an effective reducing agent to produce gold nanoparticles and nanoplates by changing the concentration of chloroauric acid.

Nanoparticle Synthesis Using Algae

There are only few reports of algae being used for the biosynthesis of metallic nanoparticles. Spirulina platensis has been reported in the preparation of gold and silver nanoparticles. In addition, Tetraselmis suecica, marine microalgae was also used to manufacture gold nanoparticles using chlorauric solution.

Researchers have demonstrated the synthesis of single-crystalline hexagonal and triangular gold nanoparticles by treating aqueous chloroauric solution with the extract of Chlorella vulgaris at room temperature. This research revealed that proteins play a vital role in the reduction and capping of gold nanoparticles.

Nanoparticle Synthesis Using Plants

Plants have shown great potential in the detoxification and accumulation of heavy metals over the years. One of the first reports on effective synthesis of gold and silver nanoparticles used alfalfa plants grown in a target metal-salt-rich environment. Nanoparticle synthesis was achieved within the living plants through an uptake of gold and silver ions from solid media.

In another research project, biosynthesis of silver nanoparticles was carried out by treating Cycas leaf extract with silver nitrate solution.

In addition, silver nanoparticles with high antimicrobial properties were reported to be synthesized using commercially available plant powders, such as Citrus sinensis, Centella asiatic, Syzygium cumini and Solanum tricobatum.


Nanotechnology is currently one of the most significant research areas in material science. For years, scientists have continuously explored various biosynthetic methods to produce nanoparticles without releasing any hazardous or toxic substances.

The use of various organisms such as bacteria, fungi, yeasts, plants in the preparation of metal nanoparticles under mild reaction conditions has drawn attention from a wider scientific community due to its rapid, economical, eco-friendly, single-step protocol.

However, scientists feel that more research needs to be focused on tailoring the electronic, electrical and optical properties of nanoparticles synthesized using eco-friendly methods, by controlling their shape and size.

Sources and Further Reading

Stuart Milne

Written by

Stuart Milne

Stuart graduated from the University of Wales, Institute Cardiff with a first-class honours degree in Industrial Product Design. After working on a start-up company involved in LED Lighting solutions, Stuart decided to take an opportunity with AZoNetwork. Over the past five years at AZoNetwork, Stuart has been involved in developing an industry leading range of products, enhancing client experience and improving internal systems designed to deliver significant value for clients hard earned marketing dollars. In his spare time Stuart likes to continue his love for art and design by creating art work and continuing his love for sketching. In the future Stuart, would like to continue his love for travel and explore new and exciting places.


Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Milne, Stuart. (2019, May 23). Environmentally Friendly Nanoparticle Synthesis. AZoNano. Retrieved on July 22, 2024 from https://www.azonano.com/article.aspx?ArticleID=3732.

  • MLA

    Milne, Stuart. "Environmentally Friendly Nanoparticle Synthesis". AZoNano. 22 July 2024. <https://www.azonano.com/article.aspx?ArticleID=3732>.

  • Chicago

    Milne, Stuart. "Environmentally Friendly Nanoparticle Synthesis". AZoNano. https://www.azonano.com/article.aspx?ArticleID=3732. (accessed July 22, 2024).

  • Harvard

    Milne, Stuart. 2019. Environmentally Friendly Nanoparticle Synthesis. AZoNano, viewed 22 July 2024, https://www.azonano.com/article.aspx?ArticleID=3732.

Tell Us What You Think

Do you have a review, update or anything you would like to add to this article?

Leave your feedback
Your comment type

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.