Arrowhead Research Corporation (NASDAQ: ARWR) today announced that the clinical trial being conducted by majority-owned subsidiary, Calando Pharmaceuticals, Inc. has demonstrated systemic delivery of siRNA and the succes...
Researchers at the Department of Chemistry at the Technical University of Munich (TUM) have developed a process that enables them to monitor local movements of proteins in time frames of nanoseconds to microseconds. When...
Human DNA is under constant assault from harmful agents such as ultraviolet sunlight, tobacco smoke and a myriad of chemicals, both natural and man-made. Because damage can lead to cancer, cell death and mutations, an army of proteins and enzymes are mobilized into action whenever it occurs. Therefore there is a system of DNA repair in a cell.
Asuragen, Inc., a leader in the development of molecular diagnostics, announced today the appointment of Biomedical Diagnostics SA (BMD), a leading medical diagnostic company in Europe, as its exclusive distributor of Si...
A California Institute of Technology (Caltech)-led team of researchers and clinicians has published the first proof that a targeted nanoparticle-used as an experimental therapeutic and injected directly into a patient's bloodstream-can traffic into tumors, deliver double-stranded small interfering RNAs (siRNAs), and turn off an important cancer gene using a mechanism known as RNA interference (RNAi).
The question of whether or not nanoparticles have an effect on the human body - and if so, how - is still largely unanswered. There is little information, for instance, on whether pregnant women exposed to these minute particles pass them on to their unborn babies.
Using a system of nanofluidic channels and multicolor fluorescence microscopy, a team of investigators at Cornell University has developed a method that analyzes the binding of DNA and DNA-binding proteins known as histo...
Using nanoparticles designed to recognize specific sugar-binding molecules on the surfaces of cells, a team of investigators at Michigan State University has developed a process that uses magnetic resonance imaging (MRI) to unlock the sugar-based code that identifies different types of cancer and normal cells.
If one nanoparticle is good, two may be better, especially when they are designed to cooperate with each other to diagnose and treat cancer. That finding comes from work led by Michael Sailor, Ph.D., a member of the Cent...
Virtually every patient diagnosed with breast cancer or melanoma undergoes lymph node biopsy to determine if their cancer has begun spreading in the body. Taking this biopsy involves an invasive and uncomfortable procedu...
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