This review develops an integrative framework for nanomeritics, the systematic characterization of pharmaceutical particles and structures of roughly 5 to 1000 nm, with particular attention to how size, morphology, surface properties, and biological interactions shape nanoparticle behavior. It argues for orthogonal measurement strategies that combine methods such as DLS, electron microscopy, NTA, and AF4 while also examining how nanoparticles change in biological environments.
A perspective in Next Nanotechnology examines how integrating quantum biosensors with microfluidic organ-on-a-chip platforms could enable continuous, high-resolution monitoring of electrophysiology, metabolism, and local tissue conditions. The approach could extend measurements from the millimeter to the nanoscale, but challenges in optical and microwave integration, thermal control, fabrication, and signal processing remain.
Researchers engineered DNA double-crossover tiles with precisely controlled hydrophobic segments, allowing the balance between DNA base pairing and hydrophobic association to determine the order of nanoscale assembly. Shorter hydrophobic chains favored star-like structures, while longer chains produced crosslinked spherical nucleic acids with enhanced biological stability and annealing-driven self-sorting.
Researchers converted sawdust into cellulose particles and tested them across water retention, barley growth, synthetic dye removal, and wound healing in mice. The results showed application-specific effects: sawdust retained the most water; clay plus nanocellulose supported strong barley growth; both materials decolorized selected dyes; and nanocellulose-treated wounds showed promising closure patterns that warrant further preclinical study.
Organic-based nanoplatforms are emerging as promising theranostic systems that combine diagnostic imaging with targeted treatment while addressing concerns about the persistence and toxicity of some inorganic nanomaterials. The review shows how molecular composition and nanoscale structure shape drug loading, targeting, imaging, therapeutic activity, biodegradation, and clinical potential across self-assembled, polymeric, lipid-based, carbon-based, and hybrid systems.
Researchers at Argonne are shaping the nanoscience frontier, using atomic-scale control to accelerate advances in electronics, energy storage, catalysis, sensing and medicine.
The device has the potential to last an entire lifetime, reducing the risks and costs associated with replacing the devices when their batteries fail.
A comprehensive review examined how nanomaterials could protect healthy tissues from radiation damage through targeted drug delivery, reactive oxygen species scavenging, anti-inflammatory activity, and physical radiation shielding. Although experimental studies show promising protection across several tissues and organ systems, most approaches remain preclinical, with long-term safety, biodistribution, scalability, and selective protection of healthy tissue still requiring investigation.
Researchers developed modular organ-targeting metal-phenolic network coatings that altered where diverse nanoparticles accumulated after intravenous administration in mice. By tuning metal ions, phenolic ligands, and PEG molecular weight, the researchers redirected nanoparticles toward the lungs, kidneys, heart, and brain while preserving functional mRNA delivery in coated lipid nanoparticles.
Researchers developed a scalable silicon microneedle electrode using mechanical dicing, KOH etching, and nanostructured platinum to improve dry EEG recording without conductive gels. The nanoPt coating increased electrochemically active surface area by about 15-fold, reduced electrode-skin impedance, and improved proof-of-concept EEG signal quality compared with non-nanostructured platinum-coated microneedles, although conventional wet electrodes still performed better.
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