Researchers developed an edge-supported nano-thick epidermal electronics platform that combines an approximately 500 nm sensing region with a reinforced 5 µm scaffold for easier handling, release, and reuse. The design enabled water-assisted release and highly conformal skin sensing, with low-impedance sEMG electrodes, a 0.48 ms temperature sensor, and a pressure sensor reaching 62.9 kPa?¹ sensitivity in its most sensitive range.
Researchers engineered a fuel-driven DNA origami nanosyringe that moves in approximately 14 nm steps to reversibly penetrate model lipid membranes and transport molecular cargo. The device also triggered localized DNA assembly, RNA transcription, and catalytic RNA cleavage inside synthetic cell-like vesicles.
Nanostructured titanium composites may enhance dental implants by providing antibacterial activity, enhanced bioactivity, corrosion protection, and localized drug-delivery capabilities. However, the review found that most evidence remains laboratory or preclinical, and long-term clinical studies are needed before these materials can move beyond established titanium implants.
Researchers benchmarked nanopore methylation callers across bacterial, plant, mouse, and human datasets, comparing accuracy, speed, memory use, coverage, read quality, and sensitivity to nearby modifications. Older Dorado v4r1 and RockFish models led CpG analysis, while newer Dorado models performed best overall for non-CpG 5mC, 6mA, and 4mC.
Researchers found that adding 1 wt.% nanographite produced the best balance of tensile strength, flexural strength, hardness, printability, and microstructural quality in SLA-printed UV-curable resin.
Higher nanographite concentrations caused agglomeration, defects, greater moisture uptake, and declining mechanical performance, highlighting the need for careful filler optimization.
This review demonstrates how nanozyme aptasensors combine synthetic enzyme-like nanomaterials with DNA or RNA aptamers to enhance selective biosensing across clinical, environmental, and food-safety applications. The paper compares three major sensor designs, NAISA, adsorption/desorption-based systems, and amplification-based platforms, while outlining the key challenges for point-of-care translation.
This review examines how programmable DNA nanostructures may support stroke repair by enabling targeted delivery, neuroprotection, biosensing, imaging, gene regulation, and tissue regeneration. The authors conclude that DNA nanotechnology is a promising preclinical platform, but clinical translation still depends on improving stability, safety, biodistribution, and scalable manufacturing.
Researchers developed optimized all-RNA lipid nanoparticles that delivered prime editor mRNA, epegRNA, and nicking gRNA to mouse liver, achieving 49% average Pcsk9 prime editing after one systemic dose.
This JACS Au Perspective traces how DNA origami has advanced from programmable nanoscale shapes into dynamic, hybrid platforms for biosensing, drug delivery, optoelectronics, nanofabrication, and synthetic biology. The authors highlight major advances in design, computation, and biomedical research while emphasizing that stability, scalability, biosafety, immunogenicity, and manufacturing barriers continue to limit broader translation.
Scientists review hybrid micro- and nanorobots that fuse magnetic steering with light-driven propulsion, enabling precise navigation through both tissue and water. These tiny machines promise targeted cancer therapy, biosensing, and pollutant destruction, all without onboard power or toxic fuel.
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