Posted in | News | Microscopy

X-ray Microscopy Bridges the Resolution Gap Between Optic and Electron Microscopy

In perhaps no other scientific field does the adage “form follows function” hold more true than in biology, especially the biology of living cells, which is why our knowledge of cells starts with imaging.

Berkeley Lab's Janos Kirz

Optical microscopy is limited by low spatial resolution – about 200 nanometers, and electron microscopy is limited by the poor penetration of electrons and the requirement that it be performed in a vacuum, which means cells must be sectioned off into tissue-thin slices and dehydrated. X-ray microscopy bridges the resolution gap between optic and electron microscopy, combining the best features of both to hit the sweet spot for chemical and elemental imaging.
Berkeley Lab's Janos Kirz

“Advances in X-ray sources, detectors, instrumentation and computing power are transforming X-ray microscopy from a scientific curiosity practiced by a few specialists, to a widely available form of high resolution imaging,” says Janos Kirz, scientific advisor for Lawrence Berkeley National Lab’s Advanced Light Source, a synchrotron radiation source optimized for soft x-ray and ultraviolet light.

“State-of-the-art X-ray microscopes can be used to create three-dimensional images with elemental and/or chemical sensitivity,” Kirz says. “Some instruments are also capable of creating movies, or providing stop-motion or flash images of cells and proteins in their natural hydrated state.”

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Lawrence Berkeley National Laboratory. (2019, February 11). X-ray Microscopy Bridges the Resolution Gap Between Optic and Electron Microscopy. AZoNano. Retrieved on June 15, 2024 from https://www.azonano.com/news.aspx?newsID=26724.

  • MLA

    Lawrence Berkeley National Laboratory. "X-ray Microscopy Bridges the Resolution Gap Between Optic and Electron Microscopy". AZoNano. 15 June 2024. <https://www.azonano.com/news.aspx?newsID=26724>.

  • Chicago

    Lawrence Berkeley National Laboratory. "X-ray Microscopy Bridges the Resolution Gap Between Optic and Electron Microscopy". AZoNano. https://www.azonano.com/news.aspx?newsID=26724. (accessed June 15, 2024).

  • Harvard

    Lawrence Berkeley National Laboratory. 2019. X-ray Microscopy Bridges the Resolution Gap Between Optic and Electron Microscopy. AZoNano, viewed 15 June 2024, https://www.azonano.com/news.aspx?newsID=26724.

Tell Us What You Think

Do you have a review, update or anything you would like to add to this news story?

Leave your feedback
Your comment type
Submit

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.