A systematic review of 25 studies found that green-synthesized nanoparticles can improve the antimicrobial and mechanical performance of glass ionomer cements, and some formulations also support fluoride release. The evidence came from 24 laboratory studies and one animal study, with no human clinical trials, so long-term safety and clinical effectiveness remain uncertain.
Polymer solar cells (PSCs) promise lightweight, flexible, and scalable solar energy, yet their efficiency still lags behind inorganic counterparts due to high exciton binding energy, low ambipolar carrier mobility, and substantial non-radiative recombination losses.
Alemnis has enabled a major advance in high-strain-rate micromechanical testing, reaching controlled, constant indentation strain rates of up to 100,000 s-1 (105 s-1) while maintaining quantitative load-displacement measurement.
The review examines how engineered nanoparticles and predictive tools, including PK/PD, PBPK, CFD, and AI/ML models, could improve drug delivery across the blood-brain barrier for Alzheimer’s, Parkinson’s, and Huntington’s diseases. It also identifies major barriers to clinical use, including low brain accumulation, long-term safety concerns, model validation, and differences between animal and human biology.
Researchers developed a chitosan-coated, manganese-doped bismuth ferrite nanoplatform that responds to acidic tumor conditions, supports T2 MRI monitoring, and combines chemodynamic therapy with ultrasound-triggered piezodynamic therapy. In subcutaneous U87 glioma-derived tumors in mice, the treatment markedly reduced tumor volume and prolonged survival; in vitro tests also showed pH-responsive MRI behavior, ROS generation, and enhanced transport across a BBB model.
Compounds containing gadolinium, a metal with magnetic properties that help highlight tumors, blood vessels or damaged tissue, are commonly used as contrast agents in MRI. Although these compounds have been essential for medical diagnosis for almost four decades, their use may pose a health risk for patients with kidney failure.
Creating a quantum device often begins by intentionally damaging a crystal.
Researchers developed an AI-assisted, ligand-triggered, room-temperature method to produce FAPbI3 perovskite nanocrystals, combining robotic experimentation, machine learning, and continuous-flow synthesis to improve control over particle size and uniformity. The process produced nearly 13 g of nanocrystals in 1 h, lowered estimated production costs, and yielded laboratory solar cells with power conversion efficiencies above 19% and improved operational and thermal stability.
Motion control specialist PI has released the new H-855 high-load hexapod robot family, a new modular 6-DOF positioning platform designed to precisely position and align payloads weighing up to 500 kg (1100 lbs).
This review evaluates chitosan-based wound dressings that integrate therapeutic ions, mesoporous silica nanocarriers, and superparamagnetic iron oxide nanoparticles to address infection, impaired angiogenesis, oxidative stress, and poor tissue regeneration in diabetic wounds. It argues that combining these components could enable controlled therapeutic delivery, magnetic responsiveness, imaging, and regenerative functions, while stressing that a fully integrated four-component system for diabetic wound healing has not yet been reported and still requires preclinical and clinical validation.
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