The NanoSight NS300 nanoparticle tracking analysis system is capable of visualizing and measuring particles in suspension in the size range of 10-2000nm. It is suitable for analysis of particles labeled with fluorescent quantum dots and addresses the needs of a wide range of applications including exosome and microvesicle research, protein aggregation, and drug delivery systems.
This NS300 offers multi-faceted analysis and incorporates a motorized filter wheel and a rheology feature that can measure viscosity in the range of 0-5 centipoise. The instrument also includes new features, such as a high sensitivity CMOS camera, a choice of laser block, and temperature control. It complements the NanoSight range of instruments and proves suitable for nanoparticle analysis without affecting quality or functionality.
The main features of the NanoSight NS300 are:
- Multi-faceted analysis
- Compact and easy to use
- High sensitivity CMOS camera
- A choice of laser block
- Temperature control
- Removable top plate and laser module block enable easy cleaning and assembly
- Top plate comes with replaceable sample chamber
The applications of the NanoSight NS300 are:
- Protein aggregation studies
- Fluorescently labeled particles
- Exosomes and microvesicles
- Ceramic and metallic nanoparticles
- Pharmaceutical nanoparticles - liposomes
- Cosmetics and foodstuffs
- Nanoparticles in fuels and oils
- Wear debris in lubricants
- Chemical mechanical polishing slurries
Early research on exosomes, or extracellular vesicles, focused on their role in excreting unwanted waste from cells. However, we’re now starting to understand their wider functionality in intercellular communication and the transmission of disease. The NanoSight system is playing a central role in helping us advance in this new and exciting area of research, by enabling us to size, count and track the movement of these crucial molecules in their native state.
Shawn Williams, Facility Manager and Imaging Specialist, University of Alabama