Advantages of SiMPore CytoVu Membranes Over Boyden Chambers for Cell Studies

Topics Covered

CytoVu Imaging Slides
Benefits of Using CytoVu Membranes
Applications for CytoVu

CytoVu Imaging Slides

Microporous CytoVu™ imaging slides from SiMPore act similar to a typical Boyden Chamber. At just 50nm thick, the membrane has precisely controlled 3 micrometer pores that allow a migrating cell to move easily from the apical side of the membrane to the basal side.

Benefits of Using CytoVu Membranes

Benefits of using CytoVu™ membranes from SiMPore over other commercially systems such as available Boyden Chambers include:

  • CytoVu membranes are much thinner (1000x), reducing the number of cells that get trapped in the membrane and improving the signal to noise ratio.
  • They are more permeable (100x), allowing more effective diffusion of chemoattractants.
  • You can culture cells on both sides of CytoVu membranes at the same time allowing you to study chemoattractants produced by a cell line, migration through a tissue layer, and many other applications.
  • The optically transparent nature of Cyto Membranes make it possible to directly image on the culture slide at the highest possible quality.

Applications for CytoVu

CytoVu™ is perfect for applications such as:

  • Cell Co-Culture
  • Cell Differentiation/Development
  • Microenvironment/Paracrine Signaling
  • Physical Cell-Cell Interactions
  • Migration/Invasion
  • High Quality Imaging
  • Drug Absorption
  • Polarized Cell Growth
  • Tissue Engineering

For more details on the applications and advantages of CytoVu™ products, click here.


SiMPore is a Rochester, New York-based nanotechnology company that designs and produces membranes and membrane-enabled products based on its unique patent-pending platform technology - the UltraSM® ultrathin nanoporous silicon membrane. The UltraSM® membrane is the world’s first membrane to offer both tunable nanometer-scale thickness and pore size. SiMPore is developing products that take advantage of theses one-of-a-kind features, including filters for separating and concentrating biological molecules and nanoparticles, cell culture substrates for growing cells, and electron microscopy grids for preparing and imaging samples at the nanoscale.

This information has been sourced, reviewed and adapted from materials provided by SiMPore.

For more information on this source, please visit SiMPore.


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