Advantages of SiMPore CytoVu Membranes Over Boyden Chambers for Cell Studies

Microporous CytoVu™ imaging slides from SiMPore act similar to a typical Boyden Chamber. At just 50nm thick, the membrane has precisely controlled 3 micrometer pores that allow a migrating cell to move easily from the apical side of the membrane to the basal side.

Benefits of Using CytoVu Membranes

Benefits of using CytoVu™ membranes from SiMPore over other commercially systems such as available Boyden Chambers include:

  • CytoVu membranes are much thinner (1000x), reducing the number of cells that get trapped in the membrane and improving the signal to noise ratio.
  • They are more permeable (100x), allowing more effective diffusion of chemoattractants.
  • You can culture cells on both sides of CytoVu membranes at the same time allowing you to study chemoattractants produced by a cell line, migration through a tissue layer, and many other applications.
  • The optically transparent nature of Cyto Membranes make it possible to directly image on the culture slide at the highest possible quality.

Applications for CytoVu

CytoVu™ is perfect for applications such as:

  • Cell Co-Culture
  • Cell Differentiation/Development
  • Microenvironment/Paracrine Signaling
  • Physical Cell-Cell Interactions
  • Migration/Invasion
  • High Quality Imaging
  • Drug Absorption
  • Polarized Cell Growth
  • Tissue Engineering

This information has been sourced, reviewed and adapted from materials provided by SiMPore Inc.

For more information on this source, please visit SiMPore Inc.

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