More Physiologically Relevant Co-Culture Studies with SiMPore CytoVu Membranes

Topics Covered

CytoVu Membranes
Benefits of Using CytoVu Membranes
Applications for CytoVu

CytoVu Membranes

CytoVu™ from SiMPore allows researchers to perform more physiologically relevant co-culture studies. CytoVu™ membranes are able to physically separate cells by only 50 nm while maintaining their ability to communicate through highly permeable nanopores. Previous co-culture systems separate the cells by as much ~10µm which is too much, or not at all. This makes true communication between the cells impossible. CytoVu™ allows you to culture different cell types that work in together form a more physiologically accurate model.

Benefits of Using CytoVu Membranes

Benefits of using CytoVu™ membranes include:

  • CytoVu™ membranes are thin (50 nm), allowing you to co-culture cells at relevant distances for established paracrine communication.
  • CytoVu™ membranes are highly permeable providing efficient diffusion of signals, drugs, and other molecules.
  • They allow you yo manipulate more tissue-like cultures (like a blood-brain barrier) in your experiments.
  • The optically transparent nature of CvtoVu membranes makes it possible to directly image on the culture slide at the highest possible quality.

Applications for CytoVu

CytoVu™ is perfect for applications such as:

  • Cell Co-Culture
  • Cell Differentiation/Development
  • Microenvironment/Paracrine Signaling
  • Physical Cell-Cell Interactions
  • Migration/Invasion
  • High Quality Imaging
  • Drug Absorption
  • Polarized Cell Growth
  • Tissue Engineering

For more details on the applications and advantages of CytoVu™ products, click here.


SiMPore is a Rochester, New York-based nanotechnology company that designs and produces membranes and membrane-enabled products based on its unique patent-pending platform technology - the UltraSM® ultrathin nanoporous silicon membrane. The UltraSM® membrane is the world’s first membrane to offer both tunable nanometer-scale thickness and pore size. SiMPore is developing products that take advantage of theses one-of-a-kind features, including filters for separating and concentrating biological molecules and nanoparticles, cell culture substrates for growing cells, and electron microscopy grids for preparing and imaging samples at the nanoscale.

This information has been sourced, reviewed and adapted from materials provided by SiMPore.

For more information on this source, please visit SiMPore.


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