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Ascentis Express RP-Amide Provides Improved Selectivity for Polar Compounds

Supelco, a division of Sigma-Aldrich, has expanded the Ascentis Express product line, a family of innovative HPLC columns designed to provide the analysis speed and resolving power of sub-2-micron columns with a 50% reduction in backpressure. Ascentis Express RP-Amide, an embedded polar group chemistry, provides an alternate selectivity to the conventional C18 and C8 phases.

"The combination of the RP-Amide advanced bonding chemistry and the Fused-Core(TM) particle provides a polar column for high-speed and high-resolution separations," said Wayne K. Way, Marketing Manager at Supelco in Bellefonte, PA. "The Ascentis Express RP-Amide provides improved peak shape for basic compounds."

The key technology in the Ascentis Express column is the Fused-Core particle. These high-purity silica particles measure 2.7 microns overall, with a 0.5 micron-thick porous shell. Relative to columns using conventional sub-2-micron particles, Ascentis Express columns generate comparable efficiencies but with half the backpressure.

Supelco's offering of HPLC products is one part of Sigma-Aldrich's technological and value-driven products that, combined with our services and support, provide complete analytical applications solutions.

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