Research in our lab marries aspects of physics and biology to study the properties of proteins or nucleic acids at the level of single macromolecules and molecular complexes. Experimental tools...
Article - 26 May 2005
Optical tweezers use light and lasers to manipulate objects as small as a single atom, and are mainly used by biological scientists to study DNA and molecular motors. How optical tweezers work,...
Article - 1 Dec 2003
New study shows how RNAP proofreads and corrects mistakes before they have a chance to create abnormal proteins. Posted November 25 2003
News - 28 Feb 2011
Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis.
The enzyme RNA...
News - 7 Nov 2008
How 'molecular machines' inside cells swing into action to activate genes at different times in a cell's life is revealed today (6 November) in new research published in Molecular Cell....
News - 23 Jun 2009
Researchers at the Universities of Leeds and Bristol have developed a model of how errors are corrected whilst proteins are being built.
Ensuring that proteins are built correctly is essential to...
News - 19 Oct 2012
An team of Rutgers University scientists led by Richard H. Ebright and Eddy Arnold has determined the three-dimensional structure of the transcription initiation complex, the key intermediate in the...
News - 1 Mar 2013
The human genome is contained within a vast jumble of DNA. Its 20,000 or so genes are concealed within strings of As, Ts, Gs, and Cs, and each gene must be turned on at the right time and in the right...
News - 23 Nov 2012
Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and...
News - 6 Feb 2009
EU-funded scientists in France have defined an important drug target in the influenza virus. The study, published in the journal Nature, shows a high-resolution image of a crucial protein that allows...