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Anticancer Drug Triggers Nanoparticle Formation

Paclitaxel is a powerful anticancer agent used to treat a variety of malignancies, but severe side effects limit its ultimate effectiveness and utility. To improve this drug’s pharmacological properties, researcher...

27 Sep 2008

Drug-Loaded Nanobubbles for Combining Ultrasonography and Targeted Chemotherapy

Using a combination of polymers that respond to temperature, a research team at the University of Utah has developed a multifunctional nanoparticle that can image tumors using ultrasound and simultaneously deliver cell-d...

27 Sep 2008

Blended Polymer Nanoparticles Pass Critical In Vivo Test

In an effort to overcome the drug resistance that often occurs in cancer, a team of investigators has developed a nanoparticle made of a blend of polymers that first releases a powerful anticancer drug and then delivers ...

27 Sep 2008

Carbon Nanotubes to Target Cancer Cells While Leaving Healthy Cells Untouched

Researchers at the Center for Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR), based at Stanford University, have found a new way to target cancer cells while leaving healthy cells untouched. The s...

27 Sep 2008

Nanoparticles Mapping Tumor Blood Supply in 3-D

One of the defining characteristics of solid tumors is the development of a network of new blood vessels to nourish the rapidly reproducing malignant cells. Now, using a nanoparticle targeted to those new blood vessels, ...

27 Sep 2008

Imaging and Treating Tumors using Nanoparticles, Anticancer Drug and Fluorescent Quantum Dot

By combining a magnetic nanoparticle, a fluorescent quantum dot, and an anticancer drug within a lipid-based nanoparticle, a multi-institutional research team headed by members of the National Cancer Institute's (NCI...

27 Sep 2008

Environmentally Friendly Method of Producing Gold Nanoparticles

Gold nanoparticles are everywhere. They are used in cancer treatments, automobile sensors, cell phones, blood sugar monitors and hydrogen gas production. However, until recently, scientists couldn't create the nanopa...

27 Sep 2008

New Imaging Method for Breast Cancer Utilizing Calcium Phosphate Nanoparticles and Infrared Imaging

A new imaging method for breast cancer has been developed by a team of scientists from Penn State Milton S. Hershey Medical Center and Penn State College of Medicine and the departments of Materials Science and Engineering and Physics at Penn State. Their research, utilizing encapsulated fluorescent molecules in calcium phosphate nanoparticles and non-toxic near infrared imaging (NIR), appears in the Sept. 19 on-line issue of ACS Nano.

26 Sep 2008

Discovery Points to New Avenue for Cancer Treatment

Scientists at The Wistar Institute and their colleagues have identified, for the first time, a molecule that can regulate microRNAs - short strands of RNA that play a vital role in gene expression and are closely associa...

26 Sep 2008

New Bio-Imaging Mass Spectrometry Center Aims to Unravel Molecular Complexities of Biological Systems

Understanding biology at the systems level is difficult, especially when studying complex specimens like tissue slices or communities of organisms in a biofilm. Scientists must be able to identify, quantify and locate the molecules present in the samples.

26 Sep 2008