According to a new study, the delivery of NA1, a neuroprotectant, to the brain in nanoparticles decreases stroke severity and enhances survival in a mouse model of stroke.
Kawasaki, Japan: The research group of Deputy Principal Research Scientist Dr. Satoshi Uchida (Associate Professor, Kyoto Prefectural University of Medicine) at the Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki-Japan, Abbreviation: iCONM) reported that optimized nano-micelles can induce efficient genome editing in the mouse brain.
Heart attack and stroke are the first and second leading causes of death in developed countries, respectively. As the disease often results in sudden death with few special prognostic symptoms, early diagnosis is very important. For this purpose, imaging techniques such as magnetic resonance imaging (MRI) are widely used to identify the narrowing or blockage of blood vessels.
Specific, effective, with a non-harmful and reversible action: the identikit of the ultimate biomaterial appears to match with graphene flakes.
Researchers from Cleveland Clinic's Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models.
The Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki in Japan, Abbreviation: iCONM) reported in ACS Nano (Impact Factor: 14.588 in 2019) together with the group of Prof. Yu Matsumoto of Otorhinolaryngology and Head and Neck Surgery (Prof. Tatsuya Yamasoba) and the group of Prof. Horacio Cabral of the Department of Bioengineering (Prof. Ryo Miyake) in the University of Tokyo that the efficacy of polymeric nano-micelles with different drug activation profile depends on the expression level of c-Myc, one of the major proto-oncogene, has been developed.
Researchers still have a long path to tread before they can treat Alzheimer’s Disease, partially because the protein aggregates that can turn into brain plaques, a characteristic attribute of the disease, are challenging to analyze.
The genetic tool CRISPR has been likened to molecular scissors for its ability to snip out and replace genetic code within DNA.
Glioblastoma multiforme, the most common and aggressive form of primary brain tumor, has a survival rate of just five years. It is particularly challenging to treat, with existing therapies depending on chemotherapy, radiation, surgery, and their combinations.
Muscle plays a crucial role in maintaining the human lives and is the largest organ accounting for 40% of body mass.