Posted in | Microscopy

Nikon, JEOL Collaborate to Address Correlative Light and Electron Microscopy

Nikon Instruments, Inc. is pleased to announce a strategic partnership between Nikon and JEOL to research and develop solutions to address correlative light and electron microscopy.

Overcoming resolution limits imposed by the diffraction of light has been a major breakthrough in the field of light microscopy, as evidenced by the recent 2014 Nobel Prize in Chemistry awarded to the field of "super-resolution" microscopy. With the development of super-resolution technologies there has been growing interest in the research community to correlate light-microscopy data with electron-microscopy data to further push the limits of resolution. Nikon has partnered with JEOL to address these needs.

Despite the breakthrough in resolution limit, light microscopes cannot provide the molecular level information that an electron microscope can. On the other hand, electron microscopes are traditionally restricted to fixed ("non-living") samples; a limitation that is not present in light microscopy. Light microscopes also have the advantage of enabling selective visualization of structures resulting in an extremely high level of molecular specificity. The Nikon-JEOL alliance was formed to research and develop tools that can correlate light and electron microscopy data, thereby combining the advantages that each technology provides.

"By bridging the gap between light microscopy and electron microscopy, Nikon strives to provide a true macro-to-molecular imaging solution," said Steve Ross, General Manager, Products and Marketing, Nikon Instruments Inc. "A solution that bridges Nikon's suite of light-based microscopes from stereo to confocal, multi-photon and super-resolution microscopes with JEOL's longstanding EM technology."


Nikon Instruments Inc. is a world leader in the development and manufacture of optical and digital imaging technology for biomedical applications. Now in its 97th year, Nikon provides complete optical systems that offer optimal versatility, performance and productivity. Cutting-edge instruments include microscopes, digital imaging products and software. Nikon Instruments is one of the microscopy and digital imaging arms of Nikon Inc., the world leader in digital imaging, precision optics and photo imaging technology. For more information, visit Product-related inquiries may be directed to Nikon Instruments at 800-52-NIKON.


JEOL is a world leader in electron optical equipment and instrumentation for high-end scientific and industrial research and development. Core product groups include electron microscopes (SEMs and TEMs), instruments for the semiconductor industry (electron beam lithography and a series of defect review and inspection tools), and analytical instruments including mass spectrometers, NMRs and ESRs.


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