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New Type of Nanocrystalline Cellulose Helps Prevent Spread of Virus into Cells

There are many viral diseases in the world for which no pharmaceutical treatment exists. These include, among others, dengue fever, which is spread by mosquitoes in the tropics, as well as a type of diarrhea, which is more familiar in Finland and is easily spread by the hands and can be dangerous especially for small children and the elderly.

16 Apr 2014

Triple-Threat Nanoparticles More Effective in Killing Ovarian Cancer Cells

Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors. In recent years, scientists have developed nanoparticles that deliver one or two chemotherapy drugs, but it has been difficult to design particles that can carry any more than that in a precise ratio.

From Massachusetts Institute of Technology 16 Apr 2014

Magnets Attract Local Anesthetic-Containing Nanoparticles to Specific Areas

A technique using anesthesia-containing nanoparticles—drawn to the targeted area of the body by magnets—could one day provide a useful alternative to nerve block for local anesthesia in patients, suggests an experimental study in the April issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

15 Apr 2014

Processing Can Affect Drug Nanocarriers Produced From Self-Assembled Polymers

Significant advances have been made in chemotherapy over the past decade, but targeting drugs to cancer cells while avoiding healthy tissues continues to be a major challenge.

15 Apr 2014

Merrimack MM-398 Study Demonstrates Feasibility of Ferumoxytol Iron Oxide Nanoparticle as a Tumor Imaging Agent

Merrimack Pharmaceuticals, Inc. today announced Phase 1 results from a clinical pilot study demonstrating that ferumoxytol*, an iron oxide nanoparticle, was well tolerated when used as a tumor contrast agent prior to MM-398 treatment. Data from the first cohort of patients in this study were presented at the American Association of Cancer Research Annual Meeting, April 5-9, 2014, in San Diego, California.

9 Apr 2014

Magnetic Nanoparticle Hyperthermia May Hold Promise for Breast Cancer Treatment

In a presentation exploring the promise of magnetic nanoparticle (mNP) hyperthermia in breast cancer treatment, Dartmouth researcher P. Jack Hoopes, DMV, PhD, reviewed preclinical studies conducted at Norris Cotton Cancer Center and discuss plans for early-phase clinical studies in humans at the annual meeting of the American Association for Cancer Research (AACR).

8 Apr 2014

Clinical Data on BIND Therapeutics’ BIND-014 Nanoparticle Drug Candidate Presented at AACR Meeting

BIND Therapeutics, Inc., a clinical-stage nanomedicine platform company developing targeted and programmable therapeutics called Accurins™, announced today that clinical data on its lead drug candidate, BIND-014, were presented at the American Association of Cancer Research (AACR) meeting.

8 Apr 2014

Sorrento to Present Data on Cynviloq-Abraxane PK Study for Ovarian Cancer

Sorrento Therapeutics, Inc. (Sorrento), a late-stage clinical oncology company developing new treatments for cancer and its associated pain, announced today that it will present data on the comparison of Cynviloq™ and Abraxane® (nab-paclitaxel) pharmacokinetics (PK) from animal studies.

7 Apr 2014

Lasers Trigger Nanoballoons to Release Drugs

Chemotherapeutic drugs excel at fighting cancer, but they're not so efficient at getting where they need to go.

4 Apr 2014

Controlled Rotation of Magnetic Nanoparticles Could Force Tumour Cells to 'Self-Destruct'

Using magnetically controlled nanoparticles to force tumour cells to 'self-destruct' sounds like science fiction, but could be a future part of cancer treatment, according to research from Lund University in Sweden.

4 Apr 2014