The University of Plymouth researchers have for the first time demonstrated the detrimental impact of nanoparticles on an animal’s brain and other areas in the central nervous system.
During their study on titanium oxide nanoparticles’ impact on fish, the scientists observed that the particles created holes or vacuoles in the brain parts and killed nerve cells in the brain. Even though researchers have already demonstrated the impact of nanoparticles in in-vitro systems and other cell cultures, this is for the first time their effect has been proved in a live vertebrate.
The findings of the study will be reported at the 6th International meeting on the Environmental Effects on Nanoparticles and Nanomaterials to be conducted at the Royal Society in London from 21 to 23 September 2011.
Lead scientist, Richard Handy stated that at this phase of the research, it is not clear whether these impacts are a result of the entry of the nanoparticles into the brain or by a secondary effect of nanoparticle reactivity or chemistry.
Professor Handy stated that it is worrisome that the impact of nanoparticles on the fish brain have some similarities with other materials such as mercury poisoning and it is a matter of concern that these materials may bio-accumulate and cause a gradual or permanent hazard to humans and wildlife.
The findings of the Professor Handy's research and that of other scientists studying the nanoparticles’ biological effects may have an influence on policy regulations for nanomaterials with regards to human safety and environmental protection.
Source: http://www.sebiology.org