AIST-NT CombiScope 1000 Scanning Probe Microscope

The CombiScope 1000 from AIST-NT is an advanced research instrument that provides the entry path for researchers in biology, spectroscopy and photonics. If you work with transparent samples either in air or in liquid towards nano-scale structures and (near-field) nano-optical properties investigation, the CombiScope 1000 is the right solution for you. It perfectly combines inverted optical and atomic force microscopies and unleashes all the power of both techniques providing the instrument adjustment and measurement automation, high resolution and high speed only available from AIST-NT. Plus it can be easily upgraded to our OmegaScope AFM-Raman system.

Extraordinary productivity and easy operation

CombiScope is equipped with a fully motorized cantilever holder and photodiode positioning that provides the automated click-on-a-button laser-to-tip alignment. This option dramatically simplifies the entire system adjustment process and provides the highest level of system adjustment reproducibility. In addition, after you instal a new cantilever of the same or even different type, you can easily relocate to the same spot (within a few microns repeatability) on your sample

Top level scanner

The CombiScope utilizes the closed loop, high-dynamics, 3-axis piezo-nanopositioning scanner from the leader in precision motion control, Physik Instrumente. The top level scanner is the heart of the system which enables it to achieve very high levels of linearity, highest possible stiffness and extremely high precision motion.

1300 nm AFM laser

The use of 1300nm AFM laser eliminates any interference with VIS light-sensitive biological and semiconductor samples. It also makes it possible to perform simultaneous AFM and fluorescence or Raman scattering measurements without any crosstalk for most popular UV-VIS-NIR (364-830 nm) excitation lasers.

Solutions for working in liquid

The standard CombiScope's sample holders accommodate all common sample substrates, including slides, cover slips and 35mm Petri dishes. The specially designed liquid cell with heating and liquid perfusion capabilities enables biological samples to be delicately maintained in their physiological environment and at temperatures up to 60°C.


The CombiScope is suited to applications such as:

  • Biology
  • Photonics
  • Spectroscopy
  • Seamless integration with SNOM/Raman /TERS techiques surface can be easily found and scanned without any extra searching steps

Other Equipment

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.