STELLARIS Cryo: Confocal CryoET Targeting With Open-Format 3D Export for Reliable ROI Localization

STELLARIS Cryo is a confocal microscope system designed to help you target your area of interest for cryo-electron tomography (CryoET) with reliable 3D localization and sample safety. Export coordinate information in an open file format for downstream lamella retrieval in cryo FIB, and export datasets in open formats (e.g., OME.TIFF) for open source usage.

Key Features

  • Enable downstream lamella retrieval in cryo‑FIB by exporting coordinate information in an open file format for subsequent retrieval steps.
  • Support open data use and interoperability by exporting datasets in an open format (e.g., OME.TIFF) for open source usage.
  • Reduce handling steps while protecting sample quality with a dedicated CryoET workflow designed to support sample viability, quality checks, and precise, reliable 3D imaging.
  • Connect confocal targeting to downstream cryo‑FIB and transfer workflows using a cryo stage and shuttle designed for seamless integration and transfer options to cryo‑FIB or vacuum cryo transfer stages.
  • Improve signal usability in cryo conditions by reducing unwanted background using fluorescence‑based approaches that help separate true signal from background noise in low‑temperature imaging.
  • Extract more information from your vitrified specimen using fluorescence‑lifetime information - adding an “extra dimension” that can help distinguish signals when spectral separation becomes harder at cryo temperatures.
  • Extend usability beyond cryo when needed because the cryo stage increases working range in non‑cryo applications, expanding the system’s use for confocal imaging.

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