Researchers developed a PLZ4-targeted, transformable peptide nanoparticle that carries the doxorubicin prodrug Leu-DOX and releases it in response to MMP9 in the tumor microenvironment. In cell studies and mouse models of bladder cancer, the platform increased tumor drug retention and produced stronger antitumor effects with fewer measured signs of doxorubicin toxicity, supporting further preclinical investigation.
By Samudrapom Dam
6 Nov 2026
Fluorescent materials usually emit a single consistent color. They are typically made from dyes or metallic components.
Colloidal quantum dots are prized for their size-tunable optical properties and solution processability, making them attractive for next-generation displays and lighting.
Researchers used plasma-engineered, (111)-textured TiN electrodes with nitrogen-rich, oxidation-resistant surfaces to reduce interfacial oxidation and lower the switching voltage of 5 nm Hf0.5Zr0.5O2 ferroelectric capacitors. The devices achieved saturated switching at 0.6 V, doubled remanent polarization to 31.5 µC/cm², showed no hard electrical breakdown through 10^12 bipolar cycles, and yielded sub-ns to low-ns switching when the measured area dependence was extrapolated to DRAM-relevant footprints.
By Dr. Noopur Jain
5 Nov 2026
Maintaining wafer geometry is critical to semiconductor processes involving precision handling, inspection, metrology, and bonding.
Researchers combined thermal, optical, mechanical, and spectroscopic measurements to map the transformation of two-photon polymerization-printed POSS/acrylate microstructures into silica glass during thermolysis. The material progresses from a rubber-like organic-inorganic network to dense fused silica, with about 40% linear shrinkage and tensile strength reaching 5.94 ± 0.45 GPa after treatment at 1000 °C.
By Dr. Noopur Jain
4 Nov 2026
Researchers developed hydro/nano-bFGF, a two-stage delivery system that combines an enzyme-responsive, cartilage-adhesive hydrogel with bFGF-loaded nanocapsules to improve drug retention, cartilage penetration, and growth factor release near chondrocytes. In human osteoarthritic cartilage explants and rodent models, the system improved matrix regeneration, cartilage structure, and joint function, while long-term safety and clinical effectiveness remain to be determined in future studies.
By Samudrapom Dam
3 Nov 2026
Creating better-performing materials comes down to having more control over their structure at the smallest possible scale.
Researchers created iSOD, a superoxide dismutase-templated ultrasmall iron oxide nanozyme that combines antioxidant activity with MRI contrast for liver fibrosis. In rat models, iSOD reduced collagen deposition and produced fibrosis-associated MRI signal differences, although larger studies and quantitative imaging validation are still needed.
By Dr. Noopur Jain
3 Nov 2026
Researchers developed a carboxymethyl cellulose-based immunonanosystem containing cobalt-substituted magnetite nanoparticles and anti-CD44 antibodies to target glioblastoma cells through enzyodynamic ferroptosis and photothermal therapy. In 2D cell cultures and 3D gliomaspheres, the system showed preferential activity against CD44-expressing glioblastoma cells, supporting further preclinical studies of its safety, delivery, and therapeutic performance.
By Samudrapom Dam
30 Oct 2026
PI’s new 6-DOF MagLev linear, rotary and AFM stages deliver contact-free, nanometer-stable motion for hybrid bonding, wafer inspection and metrology.
Researchers showed that point-defect engineering can control how copper nanoparticles exsolve from perovskite oxides, influencing exsolution yield, particle size, nucleation density, and anchoring. The study also found that oxygen vacancies are consumed during exsolution and that lattice strain can eventually limit further nanoparticle formation.
By Dr. Noopur Jain
29 Oct 2026
Researchers developed NMm@MINO, a minocycline-loaded gelatin nanoparticle coated with hybrid neutrophil–macrophage membranes to tackle bacterial infection, inflammation, and periodontal tissue damage. In laboratory and rat experiments, the platform killed bacteria, altered inflammatory responses, promoted osteogenesis-associated processes, suppressed osteoclast activity, and reduced alveolar bone loss.
By Akshatha Chandrashekar
28 Oct 2026
Researchers used spark plasma sintering technology to deposit silver, zinc, and copper metal oxide nanoparticles directly onto thermoplastic starch/carboxymethyl cellulose films, then measured changes in mechanical strength, wettability, morphology, color, and thermal behavior. The treatment increased tensile strength and reduced surface wettability, with the results varying by metal and reflecting interactions between the deposited particles and polymer functional groups.
By Samudrapom Dam
27 Oct 2026
Researchers developed glutathione-responsive EONPs that co-deliver STING and DHODH inhibitors to reprogram macrophage inflammatory metabolism in experimental sepsis. In mouse models, the treatment reduced inflammation and organ injury, improved short-term survival, and altered gut microbial metabolism, with 5-HIAA contributing to the immune response.
By Dr. Noopur Jain
26 Oct 2026