Scientists from Brigham, MIT and Women’s Hospital have designed an innovative method of forming nanoparticles that are capable of distributing drugs for diseases like cancer.
The system offers improved manipulation over the dimensions and constitution of nano particles and also helps in the production of huge amounts of similar particles.
The nano particles are produced from a generally utilized recyclable polymer than can hold huge amounts of drug particles and emit them in a restricted manner while avoiding the immune system of the body.
In the latest production system, a polymer stream moves along a microfluidic channel capable of focusing the stream three-dimensionally, separating it from the walls of the channel and also enabling production of circular nanoparticles whenever the polymer interacts with water side streams. In conventional two-dimensional production systems, polymers tend to gather along the upper and lower walls, congesting the entire system. The new production system utilizes streams of acetonitrile, an organic solvent, to avoid congestion by keeping polymers away from the walls.
The new production system was explained by the researchers in the February 22 edition of the online journal, “Advanced Materials”.